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在胃肠道解剖结构改变的患者中使用腔内置入金属支架。

Use of lumen apposing metal stents in patients with altered gastrointestinal anatomy.

机构信息

Department of Internal Medicine, Henry Ford Hospital, Detroit, Michigan.

Division of Gastroenterology and Hepatology, Maimonides Medical Center.

出版信息

Curr Opin Gastroenterol. 2023 Sep 1;39(5):348-355. doi: 10.1097/MOG.0000000000000965. Epub 2023 Jul 20.

Abstract

PURPOSE OF REVIEW

Lumen apposing metal stents (LAMS) have been increasingly used to manage patients with surgically altered anatomy (SAA), who would have otherwise required percutaneous or surgical interventions. Via the creation of de-novo anastomoses, LAMS provides a conduit to access distal parts of the gastrointestinal tract to perform various interventions.

RECENT FINDINGS

Pancreatobiliary (PB) and non-PB interventions are challenging in patients with SAA. Endoscopic ultrasound-directed transgastric endoscopic retrograde cholangiopancreatography (ERCP) (EDGE) and endoscopic ultrasound (EUS)-directed transenteric ERCP (EDEE) are effective procedures that are being increasingly utilized to perform ERCP in patient with Roux-en-Y gastric bypass (RYGB) and non-RYGB SAA, respectively. Furthermore, EUS-directed trans-gastric intervention (EDGI) is a collective term for the non-PB procedures that could be performed in patients with SAA. EDGE/EDEE/EDGI are considered relatively safe procedures, however, intra-procedural stent misdeployement, and long-term ramifications of persistent fistula and stent migration could require endoscopic or, in rare instances, surgical management.

SUMMARY

The advent of LAMS has revolutionized the therapeutic capabilities of EUS, by allowing the creation of new gastrointestinal anastomoses. With the growing body of literature, it is expected that such techniques will be more commonly performed in the community, providing less invasive and more effective treatment options for patients with SAA.

摘要

目的综述

腔内置入吻合金属支架(LAMS)越来越多地用于治疗解剖结构改变的患者(SAA),这些患者需要经皮或手术干预。通过创建新的吻合口,LAMS 为进入胃肠道的远端提供了一个通道,以进行各种介入治疗。

最近的发现

在 SAA 患者中,胰胆(PB)和非-PB 介入具有挑战性。内镜超声引导下经胃内镜逆行胰胆管造影术(EDGE)和内镜超声引导下经肠内镜逆行胰胆管造影术(EDEE)是有效的方法,越来越多地用于经 Roux-en-Y 胃旁路术(RYGB)和非-RYGB SAA 患者的 ERCP。此外,内镜超声引导下经胃介入(EDGI)是用于 SAA 患者的非-PB 介入的统称。EDGE/EDEE/EDGI 被认为是相对安全的程序,但是,支架在术中错位、持续瘘管和支架迁移的长期后果可能需要内镜或在极少数情况下需要手术管理。

总结

LAMS 的出现彻底改变了 EUS 的治疗能力,允许创建新的胃肠道吻合口。随着文献数量的增加,预计这些技术将在社区中更频繁地进行,为 SAA 患者提供更微创和更有效的治疗选择。

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