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影响 B 型主动脉夹层假腔血栓形成的因素。

Factors Affecting False Lumen Thrombosis In Type B Aortic Dissection.

机构信息

Department of Vascular and Endovascular Surgery - The First Affiliated Hospital of Guangxi Medical University, Guangxi - China.

出版信息

Arq Bras Cardiol. 2023 Jul 28;120(8):e20220939. doi: 10.36660/abc.20220939. eCollection 2023.

DOI:10.36660/abc.20220939
PMID:37531471
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10374264/
Abstract

BACKGROUND

Complete thrombosis of the false lumen facilitates remodeling of type B aortic dissection (TBAD). Morphological characteristics affect thrombosis in the false lumen.

OBJECTIVES

Discuss the factors present before admission that influence false lumen thrombosis in patients with TBAD.

METHODS

We studied 282 patients diagnosed with TBAD in our hospital between January 2008 and December 2017. We divided the subjects into a thrombotic group and a non-thrombotic group based on whether any thrombus was detectable in the false lumen. We analyzed the differences between the two groups with respect to clinical data, the vertical length of the dissection, and the diameter of the aorta. P values < 0.05 were considered statistically significantly different.

RESULTS

Significant differences between the thrombotic group and non-thrombotic group were found with respect to age (53.92 ± 11.40 vs. 50.36 ± 10.71, p = 0.009) and proportion of patients with renal insufficiency (7.83% vs. 16.38%, p = 0.026). In zones 3-9, the true lumen diameter of the thrombotic group was significantly larger than in the non-thrombotic group (p < 0.05). Binary logistic regression analysis showed that true lumen diameter in zone 5 and renal insufficiency were independent predictors of false lumen thrombosis.

CONCLUSIONS

Age and renal function were associated with thrombosis in the false lumen. Potentially, the difference between the diameter of the true lumen diameter and that of the false lumen may influence the thrombosis of the false lumen.

摘要

背景

假腔完全血栓形成有利于 B 型主动脉夹层(TBAD)的重塑。形态特征影响假腔血栓形成。

目的

探讨 TBAD 患者入院前存在的影响假腔血栓形成的因素。

方法

我们研究了 2008 年 1 月至 2017 年 12 月期间在我院诊断为 TBAD 的 282 例患者。根据假腔是否有血栓可检测,将患者分为血栓组和非血栓组。我们分析了两组之间在临床数据、夹层的垂直长度和主动脉直径方面的差异。P 值<0.05 认为有统计学差异。

结果

血栓组和非血栓组在年龄(53.92±11.40 岁 vs. 50.36±10.71 岁,p=0.009)和肾功能不全患者比例(7.83% vs. 16.38%,p=0.026)方面存在显著差异。在区域 3-9 中,血栓组的真腔直径明显大于非血栓组(p<0.05)。二元逻辑回归分析显示,区域 5 的真腔直径和肾功能不全是假腔血栓形成的独立预测因子。

结论

年龄和肾功能与假腔血栓形成有关。真腔直径和假腔直径之间的差异可能影响假腔血栓形成。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d0c9/10374264/b449f17712fc/0066-782X-abc-120-08-e20220939-gf04-en.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d0c9/10374264/ce1d15e16f97/0066-782X-abc-120-08-e20220939-gf01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d0c9/10374264/6291dcb78e44/0066-782X-abc-120-08-e20220939-gf02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d0c9/10374264/0cf35675fe4b/0066-782X-abc-120-08-e20220939-gf03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d0c9/10374264/7154b0dcd525/0066-782X-abc-120-08-e20220939-gf04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d0c9/10374264/2696bb8bb641/0066-782X-abc-120-08-e20220939-gf01-en.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d0c9/10374264/951620c9b9d3/0066-782X-abc-120-08-e20220939-gf02-en.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d0c9/10374264/3434d727e7e0/0066-782X-abc-120-08-e20220939-gf03-en.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d0c9/10374264/b449f17712fc/0066-782X-abc-120-08-e20220939-gf04-en.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d0c9/10374264/ce1d15e16f97/0066-782X-abc-120-08-e20220939-gf01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d0c9/10374264/6291dcb78e44/0066-782X-abc-120-08-e20220939-gf02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d0c9/10374264/0cf35675fe4b/0066-782X-abc-120-08-e20220939-gf03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d0c9/10374264/7154b0dcd525/0066-782X-abc-120-08-e20220939-gf04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d0c9/10374264/2696bb8bb641/0066-782X-abc-120-08-e20220939-gf01-en.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d0c9/10374264/951620c9b9d3/0066-782X-abc-120-08-e20220939-gf02-en.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d0c9/10374264/3434d727e7e0/0066-782X-abc-120-08-e20220939-gf03-en.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d0c9/10374264/b449f17712fc/0066-782X-abc-120-08-e20220939-gf04-en.jpg

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