Solid State Physics Department, Physics Research Institute, National Research Centre (NRC), 33 El-Bohouth St., Dokki, Cairo 12622, Egypt.
Physics Department, Faculty of Science, Al-Azhar University, Nasr City, Cairo 11884, Egypt.
Int J Biol Macromol. 2023 Sep 30;249:126077. doi: 10.1016/j.ijbiomac.2023.126077. Epub 2023 Aug 1.
This work discusses the physicochemical and antimicrobial characteristics of chitosan-corn starch eco-nanocomposites integrated with silica@Ag nano-spheres. These composites were synthesized through sol-gel polymerization and subsequently exposed to simulated body fluid (SBF). The incorporation of Ag into the eco-nanocomposites led to a decrease in diffuse reflectance across the entire wavelength range. The dielectric permittivity exhibited an increase up to 52.1 at a frequency of 100 kHz, while the ac conductivity reached a value of 5.2 ∗ 10 (S cm) at the same frequency for the sample with the highest Ag content. The study utilized XRD and FTIR techniques to examine the materials before and after in vitro testing and evaluated the antibacterial properties of the eco-nanocomposites against several pathogenic microorganisms, including Staphylococcus haemolyticus, Staphylococcus aureus, Klebsiella pneumoniae, and Escherichia coli, using the agar diffusion method. The eco-nanocomposites demonstrated bioactivity by forming a hydroxy appetite layer on their surfaces and were capable of releasing silver (Ag) at concentrations of 1.3, 1.9, and 2.5 mol%. This study suggests that chitosan-corn starch-SiO-based doped with Ag eco-nanocomposite has the potential for various applications, including biomedical and environmental fields, where their antibacterial properties can be utilized to combat harmful microorganisms.
本工作讨论了壳聚糖-玉米淀粉生态纳米复合材料与硅@Ag 纳米球的物理化学和抗菌特性。这些复合材料通过溶胶-凝胶聚合合成，然后暴露于模拟体液（SBF）中。Ag 的掺入导致整个波长范围内漫反射的减少。介电常数在 100 kHz 时增加到 52.1，而在相同频率下，具有最高 Ag 含量的样品的交流电导率达到 5.2 × 10（S cm）。该研究利用 XRD 和 FTIR 技术在体外测试前后检查材料，并使用琼脂扩散法评估生态纳米复合材料对几种致病性微生物（包括溶血性葡萄球菌、金黄色葡萄球菌、肺炎克雷伯菌和大肠杆菌）的抗菌性能。生态纳米复合材料通过在其表面形成羟基吸收层表现出生物活性，并能够以 1.3、1.9 和 2.5 mol%的浓度释放银（Ag）。本研究表明，基于壳聚糖-玉米淀粉-SiO 的掺杂 Ag 生态纳米复合材料具有多种应用的潜力，包括生物医学和环境领域，其抗菌性能可用于对抗有害微生物。
