College of Veterinary Medicine, Gyeongsang National University, Jinju 52828, Korea.
College of Veterinary Medicine, Seoul National University, Seoul 08826, Korea.
J Vet Sci. 2023 Jul;24(4):e57. doi: 10.4142/jvs.23029.
Siewert-Kartagener's syndrome, a type of primary ciliary dyskinesia, is a complex disease comprising situs inversus, rhinosinusitis, and bronchiectasis. Situs inversus totalis is a condition in which all organs in the thoracic and abdominal cavities are reversed. Furthermore, primary ciliary dyskinesia, an autosomal genetic disease, may coexist with situs inversus totalis. Reports on Siewert-Kartagener's syndrome in veterinary medicine are limited. We report a rare case of primary ciliary dyskinesia with Siewert-Kartagener's syndrome in a dog, concurrently infected with canine distemper virus and type-2 adenovirus. This case highlights that situs inversus totalis can cause primary ciliary dyskinesia, and concurrent infections are possible.
Siewert-Kartagener 综合征是一种原发性纤毛运动障碍，是一种复杂的疾病，包括 situs inversus、鼻旁窦炎和支气管扩张。完全性 situs inversus 是一种所有胸腔和腹腔器官都反转的情况。此外，常染色体遗传病原发性纤毛运动障碍可能与完全性 situs inversus 共存。兽医领域关于 Siewert-Kartagener 综合征的报告有限。我们报告了一例罕见的犬原发性纤毛运动障碍伴 Siewert-Kartagener 综合征的病例，该犬同时感染了犬瘟热病毒和 2 型腺病毒。该病例提示完全性 situs inversus 可引起原发性纤毛运动障碍，并且可能存在并发感染。
