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[左向右分流型先天性心脏病的微循环血管病理学]

[Pathology of microhemocirculatory vessels in congenital heart defects with left-to-right shunt].

作者信息

Nikolaeva T N, Spivak E M, Spivak L A

出版信息

Arkh Patol. 1986;48(6):8-14.

PMID:3753244
Abstract

Pathology of microcirculatory vessels of greater omentum and bulbar conjunctiva in children with congenital heart disease presenting with a left-to-right shunt was studied by biomicroscopic and morphologic methods. It has been shown that in this disorder of central hemodynamics the progressive reduction of true capillaries arises both in bulbar conjunctiva, and especially in the omentum. The authors believe that such deficit of tissue blood supply leads to reduction of density in terminal vascular networks and to the simplification of the construction of microcirculatory, in which the number of main microvessels (capillaries) increases, thus combining directly arterioles and venules, resulting in blood flow centralization and decrease of the efficiency of microcirculation.

摘要

采用生物显微镜和形态学方法,对先天性心脏病伴左向右分流患儿的大网膜和球结膜微血管进行了病理学研究。结果表明,在这种中心血流动力学紊乱中,球结膜尤其是大网膜中真毛细血管逐渐减少。作者认为,这种组织血液供应不足会导致终末血管网密度降低,微循环结构简化,其中主要微血管(毛细血管)数量增加,从而使小动脉和小静脉直接相连,导致血流集中,微循环效率降低。

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