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[基于形态学和生物显微镜数据的过敏性紫癜微血管病理学]

[Pathology of the microcirculation in Schönlein-Henoch disease according to morphological and biomicroscopic data].

作者信息

Iarygin N E, Alekseev V I, Panchenko S V

出版信息

Arkh Patol. 1979;41(11):32-8.

PMID:518364
Abstract

The state of microcirculation in hemorrhagic vasculitis was studied by morphological methods and conjunctival biomicroscopy. Inflammatory, sclerotic, and ataptative changes in terminal vessels of the internal organs and serous membranes are described. The systemic pattern of vascular pathology and selective vulnerability of the venular part (postcapillaries predominantly) in this disease were demonstrated. Morphological data reflecting the functional insufficiency (decompensation) of the local hemo- and lymph-dynamics are presented. A relative comparability of postmortem and biomicroscopic structural changes in the vessels of the microcirculatory bed was established. The method of conjunctival biomicroscopy is considered to be useful clinically not only for the elucidation of the extent of vasculitis activity but also for the evaluation of the effectiveness of treatment.

摘要

采用形态学方法和结膜生物显微镜检查对出血性血管炎的微循环状态进行了研究。描述了内脏器官和浆膜终末血管的炎症、硬化和适应性变化。证实了该疾病血管病变的全身模式以及静脉部分(主要是毛细血管后微静脉)的选择性易损性。呈现了反映局部血液和淋巴动力学功能不全(失代偿)的形态学数据。建立了微循环床血管死后结构变化与生物显微镜下结构变化的相对可比性。结膜生物显微镜检查方法不仅在临床上有助于阐明血管炎活动的程度,还可用于评估治疗效果。

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