An endogenous opioid alters neuronal plasticity to constrain cognitive flexibility.
作者信息
Olusakin Jimmy, Lobo Mary Kay
机构信息
Department of Neurobiology, University of Maryland School of Medicine, Baltimore, MD, 21201, USA.
Department of Psychiatry, University of Maryland School of Medicine, Baltimore, MD, 21201, USA.
出版信息
Mol Psychiatry. 2023 Aug;28(8):3146-3148. doi: 10.1038/s41380-023-02204-x.
Abstract
摘要
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本文引用的文献
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Kappa opioid receptor modulation of excitatory drive onto nucleus accumbens fast-spiking interneurons.κ 阿片受体对伏隔核中兴奋性传入投射到快棘神经元的调制作用。
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Dynorphin/kappa-opioid receptor control of dopamine dynamics: Implications for negative affective states and psychiatric disorders.脑啡肽/κ-阿片受体对多巴胺动态的控制：对负性情绪状态和精神障碍的影响。
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Cereb Cortex. 2018 Jan 1;28(1):103-115. doi: 10.1093/cercor/bhw353.
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Pathway- and Cell-Specific Kappa-Opioid Receptor Modulation of Excitation-Inhibition Balance Differentially Gates D1 and D2 Accumbens Neuron Activity.通路和细胞特异性κ-阿片受体对兴奋-抑制平衡的调节以不同方式控制伏隔核D1和D2神经元的活动。
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