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患者对社区药房管理和分发美沙酮治疗阿片类药物使用障碍的看法:美国的一项定性研究

Patient perspectives on community pharmacy administered and dispensing of methadone treatment for opioid use disorder: a qualitative study in the U.S.

机构信息

Department of Psychiatry and Behavioral Sciences, Duke University School of Medicine, Durham, NC, USA.

Department of Medicine, Division of General Internal Medicine, Duke University School of Medicine, Durham, NC, USA.

出版信息

Addict Sci Clin Pract. 2023 Aug 2;18(1):45. doi: 10.1186/s13722-023-00399-6.

Abstract

BACKGROUND

Pharmacy administration and dispensing of methadone treatment for opioid use disorder (PADMOUD) may address inadequate capability of opioid treatment programs (OTPs) in the US by expanding access to methadone at community pharmacies nationally. PADMOUD is vastly underutilized in the US. There is no published US study on OUD patients' perspectives on PADMOUD. Data are timely and needed to inform the implementation of PADMOUD in the US to address its serious opioid overdose crisis.

METHODS

Patient participants of the first completed US trial on PADMOUD through electronic prescribing for methadone (parent study) were interviewed to explore implementation-related factors for PADMOUD. All 20 participants of the parent study were invited to participate in this interview study. Each interview was recorded and transcribed verbatim. Thematic analysis was conducted to identify emergent themes.

RESULTS

Seventeen participants completed the interview. Patients' perspectives on PADMOUD were grouped into five areas. Participants reported feasibility of taking the tablet formulation of methadone at the pharmacy and identified benefits from PADMOUD (e.g., better access, efficiency, convenience) compared with usual care at the OTP. Participants perceived support for PADMOUD from their family/friends, OTP staff, and pharmacy staff. PADMOUD was perceived to be a great option for stable patients with take-home doses and those with transportation barriers. The distance (convenience), office hours, and the cost were considered factors most influencing their decision to receive methadone from a pharmacy. Nonjudgmental communication, pharmacists' training on methadone treatment, selection of patients (stable status), workflow of PADMOUD, and protection of privacy were considered key factors for improving operations of PADMOUD.

CONCLUSION

This study presents the first findings on patient perspectives on PADMOUD. Participants considered pharmacies more accessible than OTPs, which could encourage more people to receive methadone treatment earlier and help transition stable patients from an OTP into a local pharmacy. The findings have timely implications for informing implementation strategies of PADMOUD that consider patients' views and needs.

摘要

背景

药剂管理和为阿片类药物使用障碍(OUD)患者提供美沙酮治疗(PADMOUD)可以通过在全国社区药店扩大美沙酮的供应,来解决美国阿片类药物治疗项目(OTP)能力不足的问题。PADMOUD 在 美国的利用率非常低。目前尚无美国关于 OUD 患者对 PADMOUD 看法的研究。目前需要及时获取数据,以便为美国实施 PADMOUD 提供信息,以应对严重的阿片类药物过量危机。

方法

通过电子处方为美沙酮(母研究)完成的美国首个 PADMOUD 试验的患者参与者接受了访谈,以探讨 PADMOUD 的实施相关因素。母研究的所有 20 名参与者均受邀参加了这项访谈研究。每次访谈都进行了录音和逐字记录。采用主题分析法识别出新兴主题。

结果

17 名参与者完成了访谈。患者对 PADMOUD 的看法分为五个方面。参与者报告了在药房服用美沙酮片剂制剂的可行性,并认为与 OTP 常规护理相比,从 PADMOUD 中获得了益处(例如,更好的可及性、效率和便利性)。参与者认为家人/朋友、OTP 工作人员和药房工作人员都支持 PADMOUD。他们认为 PADMOUD 是稳定患者带剂量回家和有交通障碍患者的一个绝佳选择。距离(便利性)、办公时间和费用被认为是影响他们在药房接受美沙酮治疗的最重要因素。非评判性沟通、药剂师接受美沙酮治疗的培训、患者选择(稳定状态)、PADMOUD 的工作流程以及隐私保护被认为是改善 PADMOUD 运营的关键因素。

结论

本研究首次提出了患者对 PADMOUD 的看法。参与者认为药房比 OTP 更方便,这可能会鼓励更多的人更早地接受美沙酮治疗,并帮助稳定的患者从 OTP 过渡到当地的药房。这些发现对于告知 PADMOUD 的实施策略具有及时意义,这些策略考虑了患者的观点和需求。

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