[Correlations between variations in vigilance, E.E.G. activity, respiration, and clonicity in a case of Jakob-Creutzfeldt's disease (author's transl)].

Diurnal polygraphic recordings in a 72 year old women with Jakob-Creutzfeldt's disease (confirmed by anatomical and pathological examinations), showed correlations between modifications in respiration and myoclonic activity, and somnolent episodes. Falling asleep was marked by the replacement of periodic paroxystic activity by diffuse and irregular theta activity; the brusts of clonicity were interrupted at the same time as the paroxystic complexes; a more or less marked hypopnea accompanied most of these episodes, but the bradycardia was inconstant. The close temporal correlations between the variations in vigilance, respiration, periodic E.E.G. activity, and clonicity suggested the existence of a common triggering mechanism, the nature of which has still to be elucidated.