Terzano M G, Mancia D, Zacchetti O, Manzoni G C
Ital J Neurol Sci. 1981 Aug;2(3):243-54. doi: 10.1007/BF02335404.
The diagnostic value of the EEG in Creutzfeldt-Jakob disease is based not only on the presence of a typical pattern of periodic discharges but also on the appearance of cyclic changes in the EEG. The pattern of the cyclic EEG changes was analysed in 9 patients with Creutzfeldt-Jakob disease. The changes appear when the level of wakefulness is reduced. The alternating pattern rate increases as the disease progresses and accounts for as much as 100 per cent of the tracing when the patient is in coma. During the cyclic changes the cardiorespiratory rate is always higher in phase A than in phase B. Hypertonic fits and most myoclonic jerks are present only in the A-phase, whereas partial myoclonus and fasciculations are present in both phases. The cyclic change pattern in Creutzfeldt-Jakob disease reveals a progressive. The cyclic change pattern in Creutzfeldt-Jakob disease reveals a progressive, serious involvement of the waking system.
脑电图在克雅氏病中的诊断价值不仅基于典型的周期性放电模式，还基于脑电图的周期性变化表现。对9例克雅氏病患者的脑电图周期性变化模式进行了分析。这些变化在觉醒水平降低时出现。交替模式率随着疾病进展而增加，当患者处于昏迷状态时，该模式在描记图中所占比例高达100%。在周期性变化过程中，A期的心肺率始终高于B期。强直发作和大多数肌阵挛性抽搐仅出现在A期，而部分肌阵挛和肌束震颤在两个阶段均有出现。克雅氏病中的周期性变化模式显示出一种进展性。克雅氏病中的周期性变化模式显示出觉醒系统的进行性、严重受累。
