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利用机器学习评估患者的中风风险:来自四川和重庆的新视角。

Evaluating the Stroke Risk of Patients using Machine Learning: A New Perspective from Sichuan and Chongqing.

作者信息

Zheng Jin, Xiong Yao, Zheng Yimei, Zhang Haitao, Wu Rui

机构信息

Institute of Traditional Chinese Medicine, Sichuan Academy of Chinese Medicine Sciences, Chengdu, China.

Department of Neurology, The Third People's Hospital of Chengdu & The Affilliate Hosipital of Southwest Jiaotong University, Chengdu, China.

出版信息

Eval Rev. 2024 Apr;48(2):346-369. doi: 10.1177/0193841X231193468. Epub 2023 Aug 3.

Abstract

Stroke is the leading cause of death and disability among people in China, and it leads to heavy burdens for patients, their families and society. An accurate prediction of the risk of stroke has important implications for early intervention and treatment. In light of recent advances in machine learning, the application of this technique in stroke prediction has achieved plentiful promising results. To detect the relationship between potential factors and the risk of stroke and examine which machine learning method significantly can enhance the prediction accuracy of stroke. We employed six machine learning methods including logistic regression, naive Bayes, decision tree, random forest, K-nearest neighbor and support vector machine, to model and predict the risk of stroke. Participants were 233 patients from Sichuan and Chongqing. Four indicators (accuracy, precision, recall and F1 metric) were examined to evaluate the predictive performance of the different models. The empirical results indicate that random forest yields the best accuracy, recall and F1 in predicting the risk of stroke, with an accuracy of .7548, precision of .7805, recall of .7619 and F1 of .7711. Additionally, the findings show that age, cerebral infarction, PM 8 (an anti-atrial fibrillation drug), and drinking are independent risk factors for stroke. Further studies should adopt a broader assortment of machine learning methods to analyze the risk of stroke, by which better accuracy can be expected. In particular, RF can successfully enhance the forecasting accuracy for stroke.

摘要

中风是中国人群死亡和残疾的主要原因,给患者、其家庭和社会带来沉重负担。准确预测中风风险对早期干预和治疗具有重要意义。鉴于机器学习的最新进展,该技术在中风预测中的应用已取得了丰硕的成果。为了检测潜在因素与中风风险之间的关系,并研究哪种机器学习方法能显著提高中风预测的准确性。我们采用了六种机器学习方法,包括逻辑回归、朴素贝叶斯、决策树、随机森林、K近邻和支持向量机,来对中风风险进行建模和预测。参与者为来自四川和重庆的233名患者。通过检查四个指标(准确率、精确率、召回率和F1指标)来评估不同模型的预测性能。实证结果表明,随机森林在预测中风风险方面具有最佳的准确率、召回率和F1值,准确率为0.7548,精确率为0.7805,召回率为0.7619,F1值为0.7711。此外,研究结果表明年龄、脑梗死、PM 8(一种抗房颤药物)和饮酒是中风的独立危险因素。未来的研究应采用更广泛的机器学习方法来分析中风风险,有望获得更高的准确率。特别是,随机森林能够成功提高中风的预测准确率。

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