School of Public Health, Haramaya University, Harar, Ethiopia.
College of Health Sciences, School of Public Health, Haramaya University, Harar, Ethiopia.
Front Public Health. 2023 Jul 18;11:1165858. doi: 10.3389/fpubh.2023.1165858. eCollection 2023.
There is improved access to Sever Acute Malnutrition management in Ethiopia; however, studies have revealed an alarming rate of defaulters' poor recovery and deaths, emphasizing the importance of researching to identify major causes. As a result, the goal of this research is to identify treatment outcome determinants and associated factors in severely malnourished children aged 6-59 months admitted to public hospitals in Eastern Ethiopia's stabilization centers.
This study used an institutional-based retrospective cohort study design with 712 children aged 6 to 59 months. Data was gathered using a Sever Acute Malnutrition registration logbook and patient charts. Participants were chosen at random from their respective healthcare facilities based on population proportion. Epi-data was entered and analyzed using STATA version 14. To identify associated factors, the Cox proportional hazard Ratio was calculated, and a -value of 0.05 at the 95% confidence interval was considered statistically significant.
This study revealed that only 70.65% (95% CI = 67.19, 73.88) of the children were cured while 17.84% defaulted from the management and 5.90% died. Children who did not have tuberculosis (AHR = 1.58, 95%CI:1.04, 2.40), anemia (AHR = 1.31, 95% CI:1.03, 1.68), Kwash dermatosis (AHR = 1.41, 95%CI:1.04, 1.91), or on NG-tube (AHR = 1.71, 95%CI:1.41, 2.08) were more likely to be cured from SAM.
This study discovered that the cure rate is extremely low and the defaulter rate is extremely high. As a result, intervention modalities that address the identified factor are strongly recommended to accelerate the rate of recovery in Eastern Ethiopia.
埃塞俄比亚严重急性营养不良的管理已得到改善；然而，研究显示，大量的退出治疗者恢复不良和死亡，这强调了研究确定主要原因的重要性。因此，本研究的目的是确定在埃塞俄比亚东部公共医院稳定中心接受治疗的 6-59 月龄严重营养不良儿童的治疗结局决定因素和相关因素。
本研究采用基于机构的回顾性队列研究设计，共有 712 名 6 至 59 月龄的儿童参与。使用严重急性营养不良登记日志和患者图表收集数据。根据人口比例，从各自的医疗机构中随机选择参与者。使用 Epi-data 输入和分析数据，并使用 STATA 版本 14 进行分析。为了确定相关因素，计算了 Cox 比例风险比，置信区间为 95%，值为 0.05 时认为具有统计学意义。
本研究显示，只有 70.65%（95%CI=67.19，73.88）的儿童得到治愈，而 17.84%的儿童退出管理，5.90%的儿童死亡。未患结核病（AHR=1.58，95%CI：1.04，2.40）、贫血（AHR=1.31，95%CI：1.03，1.68）、夸什皮肤病（AHR=1.41，95%CI：1.04，1.91）或使用鼻胃管（AHR=1.71，95%CI：1.41，2.08）的儿童更有可能从严重急性营养不良中治愈。
本研究发现，治愈率极低，退出率极高。因此，强烈建议采用干预措施来解决已确定的因素，以加速埃塞俄比亚东部的康复速度。
