Fitness and the risk of illness and "spectrum disorder" in offspring, parents, and siblings.

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作者信息

Kendler K S

出版信息

Behav Genet. 1986 Jul;16(4):417-31. doi: 10.1007/BF01074261.

DOI:10.1007/BF01074261

PMID:3753372

Abstract

摘要

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Fitness and the risk of illness and "spectrum disorder" in offspring, parents, and siblings.

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The calculation of morbid risk in parents of index cases, as applied to a family sample of schizophrenics.对索引病例父母发病风险的计算，应用于精神分裂症患者的家庭样本。

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Is there an increase of reproductive rates in schizophrenics? I. Critical review of the literature.

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Am J Hum Genet. 1982 Jul;34(4):630-49.

Genetic models of schizophrenia.精神分裂症的遗传模型。

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Heritable genetic variation via mutation-selection balance: Lerch's zeta meets the abdominal bristle.通过突变-选择平衡产生的可遗传基因变异：勒尔奇ζ函数与腹部刚毛

Theor Popul Biol. 1984 Apr;25(2):138-93. doi: 10.1016/0040-5809(84)90017-0.

Estimating morbidity risks in relatives: the effect of reduced fertility.评估亲属的发病风险：生育力下降的影响。

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