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羊膜与颊脂垫治疗口腔黏膜下纤维化的疗效比较

Comparison of the Efficacy of Amniotic Membrane Versus Buccal Fat Pad in Treatment of Oral Submucous Fibrosis.

作者信息

Sharma Shipra, Mehra Hemant, Gupta Hemant, Agarwal Rashmi, Gangwar Ankit, Kumar Abhigyan

机构信息

Department of Oral and Maxillofacial Surgery, Babu Banarsi Das College of Dental Sciences, BBD City, Faizabad Road, Lucknow, 226028 India.

出版信息

J Maxillofac Oral Surg. 2023 Sep;22(3):525-532. doi: 10.1007/s12663-022-01709-2. Epub 2022 Apr 19.

Abstract

BACKGROUND

Oral and maxillofacial surgery deals with wide range of oral defects, wound closure, tissue resection, and tissue reconstruction. The purpose of our study is to use amniotic membrane for closure of post surgery defect in patient of oral submucous fibrosis to utilize its growth factor and scaffold nature for effective healing and to evaluate effectiveness of amniotic membrane in treatment outcome. The objectives are to compare post-operative mouth opening, healing of amniotic membrane and buccal fat pad.

MATERIAL AND METHOD

Diagnosed patients with OSMF are divided into two surgical site Group I ( = 5patients)-Left side buccal mucosa in which resection of fibrous band with coronoidectomy followed by reconstruction of the mucosal defect with BFP. Group II-Right side buccal mucosa in which resection of fibrous band with coronoidectomy followed by reconstruction of the mucosal defect with freeze dried irradiated amniotic membrane.

RESULT

This study suggested that in comparison to buccal fat pad flap, the HAM graft is a better option for oral reconstruction in terms of infection, graft failure, MMO, inflammation, pain. Outcome indicated that the HAM is biologically ideal graft for oral wounds and could be used as clinical alternative for various repair surgery for oral defects.

CONCLUSION

The amniotic membrane was found easy to handle and easy to use with inherent hemostatic property which is observed in all patients. No patients had shown any evidence of any complications. Good pain control observed in patients throughout postoperative period.

摘要

背景

口腔颌面外科涉及广泛的口腔缺损、伤口闭合、组织切除和组织重建。我们研究的目的是使用羊膜来闭合口腔黏膜下纤维化患者的术后缺损,利用其生长因子和支架特性实现有效愈合,并评估羊膜在治疗效果中的有效性。目标是比较术后张口度、羊膜和颊脂垫的愈合情况。

材料与方法

确诊为口腔黏膜下纤维化的患者被分为两个手术部位组。第一组(n = 5例患者)为左侧颊黏膜,切除纤维带并行冠突切除术,随后用颊脂垫重建黏膜缺损。第二组为右侧颊黏膜,切除纤维带并行冠突切除术,随后用冻干辐照羊膜重建黏膜缺损。

结果

本研究表明,与颊脂垫瓣相比,就感染、移植物失败、最大张口度、炎症、疼痛而言,人羊膜移植是口腔重建的更好选择。结果表明,人羊膜是口腔伤口的理想生物移植物,可作为口腔缺损各种修复手术的临床替代方法。

结论

发现羊膜易于操作和使用,所有患者均具有内在止血特性。没有患者出现任何并发症的迹象。在整个术后期间观察到患者的疼痛得到良好控制。

相似文献

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Comparative Evaluation of Reconstructive Methods in Oral Submucous Fibrosis.口腔黏膜下纤维化重建方法的比较评估
J Maxillofac Oral Surg. 2021 Dec;20(4):597-606. doi: 10.1007/s12663-020-01493-x. Epub 2021 Jan 23.

本文引用的文献

4
Use of amnion as a graft material in vestibuloplasty: a clinical study.羊膜在前庭成形术中作为移植材料的应用:一项临床研究。
Br J Oral Maxillofac Surg. 2012 Sep;50(6):545-9. doi: 10.1016/j.bjoms.2011.09.022. Epub 2011 Oct 24.
10
Use of amnion as a graft material in vestibuloplasty: a preliminary report.羊膜作为移植材料在前庭成形术中的应用:初步报告。
Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2004 May;97(5):574-8. doi: 10.1016/S107921040400006X.

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