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基于深度学习和胎心监护数据的胎儿状态实时分类。

Real-time Classification of Fetal Status Based on Deep Learning and Cardiotocography Data.

机构信息

AI Center, Korea University College of Medicine, Seoul, Korea.

Department of Obstetrics & Gynecology, Korea University College of Medicine, Seoul, Korea.

出版信息

J Med Syst. 2023 Aug 3;47(1):82. doi: 10.1007/s10916-023-01960-1.

DOI:10.1007/s10916-023-01960-1
PMID:37535172
Abstract

This study uses convolutional neural networks (CNNs) and cardiotocography data for the real-time classification of fetal status in the mobile application of a pregnant woman and the computer server of a data expert at the same time (The sensor is connected with the smartphone, which is linked with the web server for the woman and the computer server for the expert). Data came from 5249 (or 4833) cardiotocography traces in Anam Hospital for the mobile application (or the computer server). 150 data cases of 5-minute duration were extracted from each trace with 141,001 final cases for the mobile application and for the computer server alike. The dependent variable was fetal status with two categories (Normal, Abnormal) for the mobile application and three categories (Normal, Middle, Abnormal) for the computer server. The fetal heart rate served as a predictor for the mobile application and the computer server, while uterus contraction for the computer server only. The 1-dimension (or 2-dimension) Resnet CNN was trained for the mobile application (or the computer server) during 800 epochs. The sensitivity, specificity and their harmonic mean of the 1-dimension CNN for the mobile application were 94.9%, 91.2% and 93.0%, respectively. The corresponding statistics of the 2-dimension CNN for the computer server were 98.0%, 99.5% and 98.7%. The average inference time per 1000 images was 6.51 micro-seconds. Deep learning provides an efficient model for the real-time classification of fetal status in the mobile application and the computer server at the same time.

摘要

这项研究使用卷积神经网络 (CNN) 和胎儿监护图数据,实时分类孕妇移动应用程序和数据专家计算机服务器中的胎儿状态(传感器与智能手机相连,智能手机与妇女的网络服务器和专家的计算机服务器相连)。数据来自 Anam 医院的 5249 条(或 4833 条)胎儿监护图轨迹,用于移动应用程序(或计算机服务器),从每条轨迹中提取 150 个 5 分钟时长的数据案例,最终得到 141001 个案例,移动应用程序和计算机服务器的数据案例相同。因变量为胎儿状态,移动应用程序有两个类别(正常、异常),计算机服务器有三个类别(正常、中等、异常)。胎儿心率为移动应用程序和计算机服务器提供预测因子,而子宫收缩仅为计算机服务器提供预测因子。一维(或二维)Resnet CNN 为移动应用程序(或计算机服务器)进行了 800 个时期的训练。一维 CNN 移动应用程序的敏感性、特异性和调和平均值分别为 94.9%、91.2%和 93.0%。计算机服务器二维 CNN 的对应统计数据分别为 98.0%、99.5%和 98.7%。每 1000 张图像的平均推断时间为 6.51 微秒。深度学习为移动应用程序和计算机服务器的胎儿状态实时分类提供了一种高效的模型。

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引用本文的文献

1
Labor management and neonatal outcomes in cardiotocography categories II and III (Review).胎心监护II类和III类中的产时管理与新生儿结局(综述)
Med Int (Lond). 2024 Apr 1;4(3):27. doi: 10.3892/mi.2024.151. eCollection 2024 May-Jun.

本文引用的文献

1
DeepFHR: intelligent prediction of fetal Acidemia using fetal heart rate signals based on convolutional neural network.深度胎儿 HR(DeepFHR):基于卷积神经网络的胎儿心率信号胎儿酸中毒智能预测。
BMC Med Inform Decis Mak. 2019 Dec 30;19(1):286. doi: 10.1186/s12911-019-1007-5.
2
Computer-Aided Diagnosis System of Fetal Hypoxia Incorporating Recurrence Plot With Convolutional Neural Network.结合递归图与卷积神经网络的胎儿缺氧计算机辅助诊断系统
Front Physiol. 2019 Mar 12;10:255. doi: 10.3389/fphys.2019.00255. eCollection 2019.
3
Electronic fetal monitoring or cardiotocography, 50 years later: what's in a name?
50年后的电子胎儿监护或胎心宫缩图:名称有何含义?
Am J Obstet Gynecol. 2018 Jun;218(6):545-546. doi: 10.1016/j.ajog.2018.03.011.
4
FIGO consensus guidelines on intrapartum fetal monitoring: Cardiotocography.国际妇产科联盟(FIGO)关于产时胎儿监测的共识指南:胎心监护
Int J Gynaecol Obstet. 2015 Oct;131(1):13-24. doi: 10.1016/j.ijgo.2015.06.020.
5
The 2008 National Institute of Child Health and Human Development workshop report on electronic fetal monitoring: update on definitions, interpretation, and research guidelines.2008年美国国立儿童健康与人类发展研究所电子胎儿监护研讨会报告:定义、解读及研究指南的更新
Obstet Gynecol. 2008 Sep;112(3):661-6. doi: 10.1097/AOG.0b013e3181841395.