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Purification of a desmethylimipramine and debrisoquine hydroxylating cytochrome P-450 from human liver.

作者信息

Birgersson C, Morgan E T, Jörnvall H, von Bahr C

出版信息

Biochem Pharmacol. 1986 Sep 15;35(18):3165-6. doi: 10.1016/0006-2952(86)90403-x.

DOI:10.1016/0006-2952(86)90403-x
PMID:3753522
Abstract
摘要

相似文献

1
Purification of a desmethylimipramine and debrisoquine hydroxylating cytochrome P-450 from human liver.从人肝脏中纯化去甲丙咪嗪和异喹胍羟化细胞色素P-450
Biochem Pharmacol. 1986 Sep 15;35(18):3165-6. doi: 10.1016/0006-2952(86)90403-x.
2
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In vitro evidence against the oxidation of quinidine by the sparteine/debrisoquine monooxygenase of human liver.关于人肝脏中司巴丁/异喹胍单加氧酶对奎尼丁氧化作用的体外证据。
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A human cytochrome P-450 characterized by inhibition studies as the sparteine-debrisoquine monooxygenase.一种通过抑制研究鉴定为司巴丁-异喹胍单加氧酶的人细胞色素P-450。
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Debrisoquine-type polymorphism of drug oxidation: purification from human liver of a cytochrome P450 isozyme with high activity for bufuralol hydroxylation.药物氧化的异喹胍型多态性：从人肝脏中纯化出对丁呋洛尔羟化具有高活性的一种细胞色素P450同工酶。
FEBS Lett. 1984 Aug 6;173(2):287-90. doi: 10.1016/0014-5793(84)80792-9.

引用本文的文献

1
The effect of carbamazepine on the 2-hydroxylation of desipramine.
Psychopharmacology (Berl). 1995 Feb;117(4):413-6. doi: 10.1007/BF02246212.
2
Quinidine inhibits the 2-hydroxylation of imipramine and desipramine but not the demethylation of imipramine.
Eur J Clin Pharmacol. 1989;37(2):155-60. doi: 10.1007/BF00558224.
3
Debrisoquine oxidative phenotyping and psychiatric drug treatment.异喹胍氧化表型分析与精神科药物治疗
Eur J Clin Pharmacol. 1989;36(1):53-8. doi: 10.1007/BF00561023.
4
Clinical pharmacokinetics of imipramine and desipramine.丙咪嗪和地昔帕明的临床药代动力学
Clin Pharmacokinet. 1990 May;18(5):346-64. doi: 10.2165/00003088-199018050-00002.
5
Recent developments in hepatic drug oxidation. Implications for clinical pharmacokinetics.肝脏药物氧化的最新进展。对临床药代动力学的影响。
Clin Pharmacokinet. 1990 Mar;18(3):220-39. doi: 10.2165/00003088-199018030-00004.