Ghadially F N, Wedge J H, Lalonde J M
J Bone Joint Surg Br. 1986 Jan;68(1):106-10. doi: 10.1302/0301-620X.68B1.3753606.
A longitudinal incision resembling a bucket-handle tear was made in the menisci of 8 rabbits, 6 dogs, 11 pigs and 12 sheep. In some of the animals of each species the cut was repaired by suturing, and in others it was not. Gross inspection, as well as examination by light and electron microscopy, showed that no healing had occurred after six months in the sutured or the unsutured wounds and that the meniscus was incapable of significant intrinsic repair. In a second experiment longitudinal, transverse and T-shaped cuts were made in the menisci of 12 sheep, and a flap of synovium was sutured into the wound. Three months later there was clear evidence of healing by the formation of cartilaginous tissue. Examination by light and electron microscopy showed that the newly formed repair tissue, possibly derived by metaplasia from the synovium, had a morphology intermediate between hyaline cartilage and fibrocartilage. Synovial implantation may therefore be considered as an alternative to meniscectomy in the management of the torn meniscus.
在8只兔子、6只狗、11头猪和12只羊的半月板上制作了类似桶柄状撕裂的纵向切口。在每个物种的一些动物中，切口通过缝合进行修复，而在其他动物中则不进行缝合。大体检查以及光镜和电镜检查显示，缝合或未缝合的伤口在六个月后均未愈合，半月板无法进行显著的自身修复。在第二项实验中，在12只羊的半月板上制作了纵向、横向和T形切口，并将一块滑膜瓣缝合到伤口中。三个月后，有明确证据表明通过软骨组织的形成实现了愈合。光镜和电镜检查显示，新形成的修复组织可能由滑膜化生而来，其形态介于透明软骨和纤维软骨之间。因此，在处理撕裂的半月板时，滑膜植入可被视为半月板切除术的一种替代方法。
