Department of Pediatrics, Northwestern University Feinberg School of Medicine; Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL, USA.
Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL, USA.
Clin Perinatol. 2023 Sep;50(3):557-573. doi: 10.1016/j.clp.2023.04.004. Epub 2023 May 26.
Use of parenteral nutrition (PN) in the neonatal intensive care unit (NICU) requires evaluating the need for central venous catheters, potential drug incompatibilities, unintentional exposures, and suboptimal energy and nutrient intake during the transition to full enteral nutrition. Risks of photooxidation reactions in PN components, refeeding syndrome, and excess early amino acid intake should prompt the reevaluation of routine practices. The goal of this paper is to review the practicalities, challenges, and conundrums of administering PN in the NICU.
在新生儿重症监护病房(NICU)使用肠外营养(PN)需要评估中心静脉导管的需求、潜在的药物不相容性、非故意暴露以及在过渡到完全肠内营养期间的能量和营养素摄入不足。PN 成分的光氧化反应、再喂养综合征和早期氨基酸摄入过多的风险应促使重新评估常规实践。本文的目的是回顾在 NICU 中给予 PN 的实际情况、挑战和难题。