Wrenn Rebekah H, Trubiano Jason A
Duke University Medical Center, Durham, NC, USA; Duke Center for Antimicrobial Stewardship and Infection Prevention, Durham, NC, USA.
Department of Infectious Diseases, Centre for Antibiotic Allergy and Research, Austin Health, Melbourne, Australia; Department of Infectious Diseases, University of Melbourne, at The Peter Doherty Institute for Infection and Immunity, Victoria 3000, Australia; The National Centre for Infections in Cancer, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.
Infect Dis Clin North Am. 2023 Dec;37(4):793-822. doi: 10.1016/j.idc.2023.06.005. Epub 2023 Aug 1.
There is international evidence that penicillin allergies are associated with inferior prescribing and patient outcomes. A host of tools now exist from assessment (risk assessment tools, clinical decision rules) to delabeling (the removal of a beta-lactam allergy via testing or medical reconciliation) to reduce the impact of these "labels" in the hospital and community setting, as a primary antimicrobial stewardship intervention.
国际上有证据表明,青霉素过敏与不恰当的处方开具及患者治疗结果相关。现在有一系列从评估(风险评估工具、临床决策规则)到去除标签(通过检测或医疗核对去除β-内酰胺类过敏标签)的工具,作为主要的抗菌药物管理干预措施,以减少这些“标签”在医院和社区环境中的影响。