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膝下伴浅静脉血栓和不伴浅静脉血栓的静脉曲张日间手术比较:倾向评分匹配分析。

Comparison of day surgery between varicose veins with and without superficial venous thrombosis below knee: a propensity score-matched analysis.

机构信息

Department of Cardiovascular Surgery, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Haizhu District, No.33, Yingfeng Road, Guangzhou, 510000, Guangdong Province, China.

Zhongshan School of Medicine, Sun Yat-Sen University, No.58, Zhongshan Rd.2, Guangzhou, 510080, Guangdong Province, China.

出版信息

BMC Cardiovasc Disord. 2023 Aug 3;23(1):387. doi: 10.1186/s12872-023-03398-2.

Abstract

OBJECTIVES

Development of endovenous treatment and sclerotherapy technology makes it feasible for clinicians to treat varicose veins (VV) through day surgery (DS). Superficial venous thrombosis (SVT) of lower extremities is a common complication of VV. This study aimed to investigate whether the existence of SVT below knee affect the safety and efficacy of DS for VV patients.

METHODS

This is a single-center retrospective study. Clinical data of 593 VV patients was retrospectively analyzed. Raw data were matched by the using of propensity score matching model. Operation time, technical failure, postoperative DVT, skin burns, saphenous nerve injury, subcutaneous induration, and bleeding were compared between the groups. Also, we compared VV recurrence, SVT formation, DVT events and the change of VCSS score with 12 months.

RESULTS

Fifty-nine patients complicated with SVT below knee were matched with 118 patients had VV only. Perioperative and follow-up outcomes were similar in both groups except for the number of incisions (median = 6 [5, 7] VS median = 4 [4, 5], P < 0.001). Both groups experienced a great decrease in VCSS score.

CONCLUSION

We systematically compared the clinical outcomes of DS in VV patients. Our results indicate DS is safe and effective for patients with VV, whether accompanied by SVT below the knee.

TRIAL REGISTRATION

The ClinicalTrials.gov identifier for this trial is NCT05380895 (retrospectively registered).

摘要

目的

静脉内治疗和硬化疗法技术的发展使得临床医生能够通过日间手术(DS)治疗静脉曲张(VV)。下肢浅静脉血栓形成(SVT)是 VV 的常见并发症。本研究旨在探讨膝下 SVT 的存在是否会影响 VV 患者 DS 的安全性和疗效。

方法

这是一项单中心回顾性研究。回顾性分析了 593 例 VV 患者的临床资料。使用倾向评分匹配模型对原始数据进行匹配。比较两组患者的手术时间、技术失败、术后 DVT、皮肤烧伤、隐神经损伤、皮下硬结和出血。还比较了 12 个月时 VV 复发、SVT 形成、DVT 事件和 VCSS 评分的变化。

结果

59 例膝下 SVT 合并患者与 118 例单纯 VV 患者匹配。两组围手术期和随访结果相似,除切口数量外(中位数=6 [5,7]VS 中位数=4 [4,5],P<0.001)。两组患者的 VCSS 评分均显著降低。

结论

我们系统地比较了伴有和不伴有膝下 SVT 的 VV 患者 DS 的临床结局。我们的结果表明,DS 是安全有效的,无论患者是否伴有膝下 SVT。

试验注册

本试验的 ClinicalTrials.gov 标识符为 NCT05380895(回顾性注册)。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fe8a/10401813/18ead809ccae/12872_2023_3398_Fig1_HTML.jpg

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