Wakabayashi Kohei, Suzuki Toshiaki, Sato Chisato, Nishikura Tenjin
Division of Cardiology, Cardiovascular Center, Showa University Koto-Toyosu Hospital, 5-1-38, Toyosu, Koto-ku, Tokyo 135-8577, Japan.
Eur Heart J Case Rep. 2023 Jul 21;7(8):ytad338. doi: 10.1093/ehjcr/ytad338. eCollection 2023 Aug.
Peripheral artery disease (PAD) is usually diagnosed with non-invasive arterial testing methods such as Doppler ultrasound or computed tomography angiography and treated with revascularization using contrast media, which increases the risk of contrast nephropathy and the need for subsequent renal replacement therapy, especially in patients with advanced chronic kidney disease (CKD). Therefore, it is important to identify a worthy alternative strategy for use in high-risk patients.
We present the case of a 79-year-old man with bilateral claudication and advanced CKD. The patient had a high risk of sustained reduction in renal function and requirement of renal replacement therapy in the event that contrast media was used. Therefore, we planned a zero-contrast strategy for diagnosis and treatment. The case was diagnosed as bilateral stenotic iliac disease with non-contrast magnetic resonance angiography. Zero-contrast intervention was conducted successfully under magnetic resonance angiography and intra-vascular ultrasound guidance, resulting in an excellent clinical outcome and avoidance of worsening renal function.
This zero-contrast strategy appears to be a viable alternative to angiography using contrast for diagnosis and treatment in patients with PAD and advanced CKD where contrast use is relatively contraindicated.
外周动脉疾病(PAD)通常采用多普勒超声或计算机断层血管造影等非侵入性动脉检测方法进行诊断,并使用造影剂进行血管重建治疗,这增加了造影剂肾病的风险以及后续肾脏替代治疗的需求,尤其是在晚期慢性肾脏病(CKD)患者中。因此,为高危患者确定一种值得采用的替代策略很重要。
我们报告一例79岁男性患者,患有双侧间歇性跛行和晚期CKD。如果使用造影剂,该患者肾功能持续下降及需要肾脏替代治疗的风险很高。因此,我们计划采用零造影剂策略进行诊断和治疗。通过非增强磁共振血管造影诊断该病例为双侧髂动脉狭窄疾病。在磁共振血管造影和血管内超声引导下成功实施了零造影剂干预,取得了良好的临床效果,并避免了肾功能恶化。
对于PAD和晚期CKD患者,在相对禁忌使用造影剂的情况下,这种零造影剂策略似乎是一种可行的替代造影剂血管造影用于诊断和治疗的方法。