Department of Urology, Second Xiangya Hospital, Central South University, Changsha 410011, China.
Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2023 May 28;48(5):782-788. doi: 10.11817/j.issn.1672-7347.2023.220550.
Leiomyosarcoma of urinary bladder (LMS-UB) is a highly malignant mesenchymal tumor, accounting for less than 0.5% of all bladder malignancies, with a predominant clinical presentation of hematuria. Here we report a case of low-grade LMS-UB. A 44-year-old male patient was admitted to the hospital with urodynia for 2 weeks. The patient's pelvis CT showed a mass on the right part of the bladder. For this reason, he was initially diagnosed with bladder cancer. We performed a robot-assisted laparoscopic enucleation of the bladder tumor and low-grade LMS-UB was diagnosed with the histopathological examination. He underwent 5 cycles of adjuvant chemotherapy after surgery. At 19months postoperative follow-up, the patient had no symptoms, recurrence, or distant metastasis. There is no report on the treatment of LMS-UB with minimally invasive enucleation worldwide. This case provides a new comprehensive treatment method of enucleation combined with adjuvant chemotherapy for early low-grade LMS-UB to reduce complications and improve patients' quality of life after surgery.
膀胱平滑肌肉瘤（LMS-UB）是一种高度恶性的间叶组织肿瘤，占所有膀胱恶性肿瘤的比例不到 0.5%，主要临床表现为血尿。本文报道了 1 例低级别 LMS-UB 患者。1 名 44 岁男性患者因尿痛 2 周入院。患者盆腔 CT 显示膀胱右侧有一肿块。因此，他最初被诊断为膀胱癌。我们对其进行了机器人辅助腹腔镜膀胱肿瘤剜除术，术后组织病理学检查诊断为低级别 LMS-UB。患者术后接受了 5 个周期的辅助化疗。术后 19 个月随访时，患者无任何症状、复发或远处转移。目前，全世界尚无关于微创剜除术治疗 LMS-UB 的报道。该病例为早期低级别 LMS-UB 提供了一种新的综合治疗方法，即剜除术联合辅助化疗，以减少术后并发症并提高患者的生活质量。
