ASO作者反思：一种更有效的早期乳腺癌放疗方式：术中放疗作为瘤床加量联合全乳照射 - Suppr

ASO Author Reflections: A More Effective Radiotherapy Modality for Early Breast Cancer: Intraoperative Radiotherapy as a Tumour Bed Boost Combined with Whole Breast Irradiation.

作者信息

He Jiafa, Chen Shengying, Xu Rui

机构信息

Breast Department, Guangdong Provincial Hospital of Chinese Medicine, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangdong Provincial Academy of Chinese Medical Sciences, Guangzhou, Guangdong, China.

出版信息

Ann Surg Oncol. 2023 Dec;30(13):8453-8454. doi: 10.1245/s10434-023-14057-3. Epub 2023 Aug 4.

DOI:10.1245/s10434-023-14057-3

PMID:37540328

Abstract

摘要

相似文献

ASO Author Reflections: A More Effective Radiotherapy Modality for Early Breast Cancer: Intraoperative Radiotherapy as a Tumour Bed Boost Combined with Whole Breast Irradiation.ASO作者反思：一种更有效的早期乳腺癌放疗方式：术中放疗作为瘤床加量联合全乳照射

Ann Surg Oncol. 2023 Dec;30(13):8453-8454. doi: 10.1245/s10434-023-14057-3. Epub 2023 Aug 4.

Quality of life after breast-conserving therapy and adjuvant radiotherapy for non-low-risk ductal carcinoma in situ (BIG 3-07/TROG 07.01): 2-year results of a randomised, controlled, phase 3 trial.非低危型导管原位癌保乳治疗及辅助放疗后的生活质量（BIG 3-07/TROG 07.01）：一项随机、对照、III 期临床试验的 2 年结果。

Lancet Oncol. 2020 May;21(5):685-698. doi: 10.1016/S1470-2045(20)30085-1. Epub 2020 Mar 20.

The biologic rationale for and emerging role of accelerated partial breast irradiation for breast cancer.加速部分乳腺照射在乳腺癌治疗中的生物学原理及新出现的作用。

J Am Coll Surg. 2004 Sep;199(3):479-92. doi: 10.1016/j.jamcollsurg.2004.04.019.

Local recurrence rates in breast cancer patients treated with intraoperative electron-boost radiotherapy versus postoperative external-beam electron-boost irradiation. A sequential intervention study.接受术中电子束增强放疗与术后外照射电子束增强放疗的乳腺癌患者的局部复发率。一项序贯干预研究。

Strahlenther Onkol. 2004 Jan;180(1):38-44. doi: 10.1007/s00066-004-1190-9.

Intraoperative radiotherapy during breast-conserving surgery using a miniature x-ray generator (Intrabeam®): theoretical and experimental background and clinical experience.使用微型X射线发生器（Intrabeam®）在保乳手术中进行术中放疗：理论与实验背景及临床经验

Womens Health (Lond). 2012 Jan;8(1):39-47. doi: 10.2217/whe.11.82.

Which patients don't need a tumor-bed boost after whole-breast radiotherapy?哪些患者在全乳放疗后不需要瘤床加量？

Strahlenther Onkol. 2001 Jan;177(1):33-6. doi: 10.1007/pl00002355.

Intraoperative radiation therapy or external whole-breast irradiation, which is more effective in controlling the local recurrence of breast cancer? A Weibull regression model.术中放射治疗或全乳外照射，哪种在控制乳腺癌局部复发方面更有效？一个威布尔回归模型。

Breast J. 2021 Feb;27(2):191-193. doi: 10.1111/tbj.14138. Epub 2021 Feb 1.

Intraoperative radiotherapy versus external radiotherapy for early breast cancer (ELIOT): a randomised controlled equivalence trial.早期乳腺癌术中放疗与体外放疗对比（ELIOT）：一项随机对照等效性试验。

Lancet Oncol. 2013 Dec;14(13):1269-77. doi: 10.1016/S1470-2045(13)70497-2. Epub 2013 Nov 11.

Adjuvant hypofractionated radiotherapy with weekly concomitant boost for women with early breast cancer: the clinical experience at Genoa university.辅助性每周同步推量超分割放射治疗早期乳腺癌的临床经验：热那亚大学。

Anticancer Res. 2010 Nov;30(11):4749-53.

ASO Author Reflections: The Strengths and Weaknesses of Intraoperative Radiotherapy for Early Breast Cancer and Ipsilateral Tumor Recurrence.ASO作者反思：早期乳腺癌术中放疗及同侧肿瘤复发的优缺点

Ann Surg Oncol. 2019 Dec;26(Suppl 3):660-661. doi: 10.1245/s10434-019-07658-4. Epub 2019 Jul 29.

本文引用的文献

Development and Validation of a Recurrence-Free Survival Prediction Model for Locally Advanced Esophageal Squamous Cell Carcinoma with Neoadjuvant Chemoradiotherapy.局部晚期食管鳞癌新辅助放化疗后无复发生存预测模型的建立与验证。

Ann Surg Oncol. 2024 Jan;31(1):178-191. doi: 10.1245/s10434-023-14308-3. Epub 2023 Sep 26.

Comparison of IORT (Radical and Boost Dose) and EBRT in Terms of Disease-Free Survival and Overall Survival according to Demographic, Pathologic, and Biological Factors in Patients with Breast Cancer.比较乳腺癌患者的无病生存和总体生存，根据人口统计学、病理学和生物学因素，IORT（根治剂量和加量照射）与 EBRT 的差异。

Int J Surg Oncol. 2021 Apr 16;2021:2476527. doi: 10.1155/2021/2476527. eCollection 2021.

IOERT versus external beam electrons for boost radiotherapy in stage I/II breast cancer: 10-year results of a phase III randomized study.IOERT 与外部束电子线在 I/II 期乳腺癌中的推量放疗：一项 III 期随机研究的 10 年结果。

Breast Cancer Res. 2021 Apr 13;23(1):46. doi: 10.1186/s13058-021-01424-9.

Intraoperative irradiation for early breast cancer (ELIOT): long-term recurrence and survival outcomes from a single-centre, randomised, phase 3 equivalence trial.早期乳腺癌术中放疗（ELIOT）：来自单中心、随机、3 期等效性试验的长期复发和生存结果。

Lancet Oncol. 2021 May;22(5):597-608. doi: 10.1016/S1470-2045(21)00080-2. Epub 2021 Apr 9.

Outcome of hypofractionated breast irradiation and intraoperative electron boost in early breast cancer: A randomized non-inferiority clinical trial.早期乳腺癌分次少的乳房照射和术中电子束加量照射的结果：一项随机非劣效性临床试验。

Cancer Rep (Hoboken). 2021 Oct;4(5):e1376. doi: 10.1002/cnr2.1376. Epub 2021 Apr 1.

Long term survival and local control outcomes from single dose targeted intraoperative radiotherapy during lumpectomy (TARGIT-IORT) for early breast cancer: TARGIT-A randomised clinical trial.保乳术后单次剂量靶向术中放疗（TARGIT-IORT）治疗早期乳腺癌的长期生存和局部控制结果：TARGIT-A 随机临床试验。

BMJ. 2020 Aug 19;370:m2836. doi: 10.1136/bmj.m2836.

One-step intraoperative radiotherapy optimizes conservative treatment of breast cancer with advantages in quality of life and work resumption.一步式术中放疗优化了乳腺癌的保守治疗，提高了生活质量和工作恢复率。

Breast. 2018 Jun;39:123-130. doi: 10.1016/j.breast.2018.04.004. Epub 2018 Apr 17.

Targeted intraoperative radiotherapy tumour bed boost during breast-conserving surgery after neoadjuvant chemotherapy.新辅助化疗后保乳手术期间对瘤床进行术中靶向放疗加量

Strahlenther Onkol. 2017 Jan;193(1):62-69. doi: 10.1007/s00066-016-1072-y. Epub 2016 Nov 17.

IOERT as anticipated tumor bed boost during breast-conserving surgery after neoadjuvant chemotherapy in locally advanced breast cancer--results of a case series after 5-year follow-up.保乳手术后新辅助化疗局部晚期乳腺癌中预期瘤床推量放疗（IOERT）——5 年随访后的病例系列结果。

Int J Cancer. 2015 Mar 1;136(5):1193-201. doi: 10.1002/ijc.29064. Epub 2014 Jul 10.

Lancet Oncol. 2013 Dec;14(13):1269-77. doi: 10.1016/S1470-2045(13)70497-2. Epub 2013 Nov 11.

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ASO Author Reflections: A More Effective Radiotherapy Modality for Early Breast Cancer: Intraoperative Radiotherapy as a Tumour Bed Boost Combined with Whole Breast Irradiation.

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