Eridani S, Singh A K
Oncology. 1986;43(2):107-9. doi: 10.1159/000226345.
A patient seen at presentation for Hodgkin's disease (HD) at stage IV B was successfully treated with MOPP. In remission he developed coeliac disease, controlled by dietary measures, but 26 months after the end of chemotherapy a severe dyspeptic syndrome appeared; endoscopy and barium meal suggested the presence of a gastric tumour, which was surgically removed and showed the histological features of a non-Hodgkin's lymphoma, lympho-histiocytic type. Only moderate chemotherapy was given after the operation and the patient obtained a new complete remission which has lasted 3 years so far. It is likely that the immune depression caused by HD itself and the relevant chemotherapy may have favoured the occurrence of both coeliac disease and subsequent gastric lymphoma.
一名IV B期霍奇金病（HD）患者初诊时接受MOPP方案成功治疗。缓解期他患上乳糜泻，通过饮食措施得以控制，但化疗结束26个月后出现严重消化不良综合征；内镜检查和钡餐检查提示存在胃肿瘤，手术切除后显示为非霍奇金淋巴瘤，淋巴组织细胞型的组织学特征。术后仅给予适度化疗，患者再次完全缓解，至今已持续3年。HD本身及相关化疗引起的免疫抑制可能促使了乳糜泻和随后胃淋巴瘤的发生。
