复发性霍奇金淋巴瘤与治疗相关的非霍奇金淋巴瘤同时出现。

Simultaneous presentation of relapsing Hodgkin's disease and treatment-related non-Hodgkin's lymphoma.

作者信息

Perri R T, Allen J I, Oken M M, Limas C, Kay N E

出版信息

Med Pediatr Oncol. 1985;13(3):122-5. doi: 10.1002/mpo.2950130303.

Abstract

A 55-year-old white man was diagnosed in 1975 with Hodgkin's disease stage IIA, mixed cellularity. He was treated with 4,500 rads to an inverted-Y field followed by six cycles of MOPP and remained in complete remission. In 1983 a right axillary lymph node biopsy showed recurrent Hodgkin's disease, mixed cellularity. While receiving his initial chemotherapy he developed persistent epigastric distress. Endoscopic gastric biopsy demonstrated a diffuse large-cell non-Hodgkin's lymphoma. Surface marker studies confirmed the separate identity of these two malignant lymphoproliferative processes. This represents the first reported simultaneous occurrence of relapsing Hodgkin's disease with treatment-related non-Hodgkin's lymphoma.

摘要

一名55岁的白人男性于1975年被诊断为IIA期混合细胞型霍奇金病。他接受了倒Y野4500拉德的放疗，随后进行了六个周期的MOPP方案化疗，之后一直处于完全缓解状态。1983年，右侧腋窝淋巴结活检显示复发性混合细胞型霍奇金病。在接受初始化疗期间，他出现了持续的上腹部不适。内镜下胃活检显示为弥漫性大细胞非霍奇金淋巴瘤。表面标志物研究证实了这两种恶性淋巴增殖性疾病的不同性质。这是首次报道的复发性霍奇金病与治疗相关的非霍奇金淋巴瘤同时发生的病例。