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Cell-Free DNA Detects Lung Infection in Modulator-treated People with Cystic Fibrosis.游离DNA可检测出接受调节剂治疗的囊性纤维化患者的肺部感染。
Am J Respir Crit Care Med. 2023 Nov 1;208(9):944-947. doi: 10.1164/rccm.202305-0844LE.
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Factors influencing the acquisition and eradication of early Pseudomonas aeruginosa infection in cystic fibrosis.影响囊性纤维化患者早期铜绿假单胞菌感染获得和清除的因素。
J Cyst Fibros. 2021 Jan;20(1):8-16. doi: 10.1016/j.jcf.2020.10.008. Epub 2020 Nov 7.
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TOBI Podhaler for cystic fibrosis patients with Pseudomonas aeruginosa.妥布霉素吸入粉雾剂用于患有铜绿假单胞菌的囊性纤维化患者。
Nurse Pract. 2015 Jul 15;40(7):16-7. doi: 10.1097/01.NPR.0000459736.07899.73.
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Considerations for the use of inhaled antibiotics for in people with cystic fibrosis receiving CFTR modulator therapy.对于接受CFTR调节剂治疗的囊性纤维化患者使用吸入性抗生素的考量。
BMJ Open Respir Res. 2024 May 3;11(1):e002049. doi: 10.1136/bmjresp-2023-002049.
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Antibiotic strategies for eradicating Pseudomonas aeruginosa in people with cystic fibrosis.根除囊性纤维化患者体内铜绿假单胞菌的抗生素策略。
Cochrane Database Syst Rev. 2017 Apr 25;4(4):CD004197. doi: 10.1002/14651858.CD004197.pub5.
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Standard versus biofilm antimicrobial susceptibility testing to guide antibiotic therapy in cystic fibrosis.标准抗菌药敏试验与生物膜抗菌药敏试验在指导囊性纤维化抗生素治疗中的应用
Cochrane Database Syst Rev. 2015 Mar 5(3):CD009528. doi: 10.1002/14651858.CD009528.pub3.
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Standard versus biofilm antimicrobial susceptibility testing to guide antibiotic therapy in cystic fibrosis.标准抗菌药敏试验与生物膜抗菌药敏试验用于指导囊性纤维化患者的抗生素治疗
Cochrane Database Syst Rev. 2020 Jun 10;6(6):CD009528. doi: 10.1002/14651858.CD009528.pub5.
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Standard versus biofilm antimicrobial susceptibility testing to guide antibiotic therapy in cystic fibrosis.标准抗菌药敏试验与生物膜抗菌药敏试验用于指导囊性纤维化患者的抗生素治疗
Cochrane Database Syst Rev. 2017 Oct 5;10(10):CD009528. doi: 10.1002/14651858.CD009528.pub4.
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activity of cefiderocol against isolated from cystic fibrosis patients.头孢地尔对从囊性纤维化患者中分离出的（菌株）的活性。 （原文表述不太完整，推测是这样的意思，完整准确的翻译可能需要更多上下文信息）
Microbiol Spectr. 2023 Dec 12;11(6):e0304723. doi: 10.1128/spectrum.03047-23. Epub 2023 Nov 20.
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Antibiotic strategies for eradicating Pseudomonas aeruginosa in people with cystic fibrosis.根除囊性纤维化患者体内铜绿假单胞菌的抗生素策略。
Cochrane Database Syst Rev. 2014 Nov 10(11):CD004197. doi: 10.1002/14651858.CD004197.pub4.
引用本文的文献
1
Effects of CFTR Modulators on Infections in Cystic Fibrosis.囊性纤维化跨膜传导调节因子调节剂对囊性纤维化感染的影响。
Infect Dis Rep. 2025 Jul 7;17(4):80. doi: 10.3390/idr17040080.
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Risk factors for postoperative pulmonary infections in non-small cell lung cancer: a regression-based nomogram prediction model.非小细胞肺癌术后肺部感染的危险因素：基于回归的列线图预测模型
Am J Cancer Res. 2024 Nov 15;14(11):5365-5377. doi: 10.62347/BIBD8425. eCollection 2024.
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Persistence and evolution of following initiation of highly effective modulator therapy in cystic fibrosis.高效调节剂治疗开始后囊性纤维化的持续和演变。
mBio. 2024 May 8;15(5):e0051924. doi: 10.1128/mbio.00519-24. Epub 2024 Apr 2.
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Phoenix from the Ashes: Celebrating the 2023 North American Cystic Fibrosis Conference.浴火重生：庆祝2023年北美囊性纤维化会议
Am J Respir Crit Care Med. 2023 Nov 1;208(9):909-910. doi: 10.1164/rccm.202309-1603ED.
本文引用的文献
1
Pharmacologic improvement of CFTR function rapidly decreases sputum pathogen density, but lung infections generally persist.药物改善 CFTR 功能可迅速降低痰中病原体密度，但肺部感染通常持续存在。
J Clin Invest. 2023 May 15;133(10):e167957. doi: 10.1172/JCI167957.
2
Genome Capture Sequencing Selectively Enriches Bacterial DNA and Enables Genome-Wide Measurement of Intrastrain Genetic Diversity in Human Infections.基因组捕获测序选择性富集细菌 DNA，并能够在人类感染中进行全基因组测量菌株内遗传多样性。
mBio. 2022 Oct 26;13(5):e0142422. doi: 10.1128/mbio.01424-22. Epub 2022 Sep 19.
3
Circulating microbial cell-free DNA is associated with inflammatory host-responses in severe pneumonia.循环微生物无细胞 DNA 与严重肺炎中的炎症宿主反应有关。
Thorax. 2021 Dec;76(12):1231-1235. doi: 10.1136/thoraxjnl-2020-216013. Epub 2021 Apr 22.
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Parallel Analysis of Cystic Fibrosis Sputum and Saliva Reveals Overlapping Communities and an Opportunity for Sample Decontamination.囊性纤维化痰液和唾液的平行分析揭示了重叠菌群以及样本净化的机会。
mSystems. 2020 Jul 7;5(4):e00296-20. doi: 10.1128/mSystems.00296-20.
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Cell free DNA from respiratory pathogens is detectable in the blood plasma of Cystic Fibrosis patients.呼吸道病原体的游离 DNA 可在囊性纤维化患者的血浆中检测到。
Sci Rep. 2020 Apr 23;10(1):6903. doi: 10.1038/s41598-020-63970-0.
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Improved metagenomic analysis with Kraken 2.Kraken 2 提升宏基因组分析。
Genome Biol. 2019 Nov 28;20(1):257. doi: 10.1186/s13059-019-1891-0.
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Detection of Pneumonia Pathogens from Plasma Cell-Free DNA.从血浆游离DNA中检测肺炎病原体
Am J Respir Crit Care Med. 2020 Feb 15;201(4):491-495. doi: 10.1164/rccm.201904-0905LE.
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Analytical Comparison of Methods for Extraction of Short Cell-Free DNA from Urine.尿液中短游离 DNA 提取方法的分析比较。
J Mol Diagn. 2019 Nov;21(6):1067-1078. doi: 10.1016/j.jmoldx.2019.07.002. Epub 2019 Aug 20.
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Analytical and clinical validation of a microbial cell-free DNA sequencing test for infectious disease.微生物无细胞 DNA 测序检测用于感染性疾病的分析和临床验证。
Nat Microbiol. 2019 Apr;4(4):663-674. doi: 10.1038/s41564-018-0349-6. Epub 2019 Feb 11.
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The CF-Sputum Induction Trial (CF-SpIT) to assess lower airway bacterial sampling in young children with cystic fibrosis: a prospective internally controlled interventional trial.囊性纤维化患儿下呼吸道细菌采样评估的 CF-诱导痰试验（CF-SpIT）：一项前瞻性内部对照干预性试验。
Lancet Respir Med. 2018 Jun;6(6):461-471. doi: 10.1016/S2213-2600(18)30171-1. Epub 2018 May 16.
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