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通过喂食感染红青霉的饲料对大鼠重要器官进行的生化变化研究

Biochemical changes in rat vital organs by feeding a diet infested with Penicillium rubrum Stoll.

作者信息

Chauhan R K, Singh A, Chauhan S

出版信息

Toxicol Lett. 1986 Jan;30(1):49-53. doi: 10.1016/0378-4274(86)90178-5.

DOI:10.1016/0378-4274(86)90178-5
PMID:3754067
Abstract

Weanling albino rats were fed with either a control diet or one infested with Penicillium rubrum Stoll for a period of 30 days. At the end of the experimental period, determinations of haemoglobin, total proteins and transaminases were made in blood and tissues (liver, brain and kidney). The fungus was found to render the food toxic, resulting in liver and kidney damage. The toxicity of the fungus was also evidenced by poor live weight gains and organ weights.

摘要

将断乳的白化病大鼠喂食对照饮食或感染了红色青霉(Penicillium rubrum Stoll)的饮食30天。在实验期结束时,对血液和组织(肝脏、大脑和肾脏)中的血红蛋白、总蛋白和转氨酶进行了测定。发现该真菌使食物产生毒性,导致肝脏和肾脏损伤。体重增加不佳和器官重量也证明了该真菌的毒性。

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