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基于专业和方法的肠内通路结局:单中心三年经验。

Outcomes in Enteral Access Based on Specialty and Approach: A Single-Center Three-Year Experience.

机构信息

Department of Surgery, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania.

Department of Surgery, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania.

出版信息

J Surg Res. 2023 Nov;291:567-573. doi: 10.1016/j.jss.2023.07.006. Epub 2023 Aug 2.

Abstract

INTRODUCTION

Interventional radiologic, endoscopic, and surgical approaches are commonly utilized to establish durable enteral access in adult patients. The purpose of this study is to examine differences in nutritional outcomes in a large cohort of patients undergoing enteral access creation.

METHODS

Adult patients who underwent enteral access procedures by interventional radiologists, gastroenterologists, and surgeons between 2018 and 2020 at a single institution were reviewed. Included access types were percutaneous endoscopic gastrostomy (PEG), open or laparoscopic gastrostomy, laparoscopic jejunostomy, and percutaneous gastrostomy (perc-G), percutaneous jejunostomy , or primary gastrojejunostomy.

RESULTS

912 patients undergoing enteral access cases met the criteria for inclusion. PEGs and perc-Gs were the most common procedures. PEGs had higher Charlson scores (4.5 [3.0-6.0] versus 2.0 [1.0-2.0], P = 0.007) and lower starting albumin (3.0 [2.6-3.4] versus 3.6 [3.5-3.8] g/dL, P < 0.0001). Time to goal feeds (4 [2-6] vs 4 [3-5] d, P = 0.970), delta prealbumin (3.6 [0-6.5] versus 6.2 [2.3-10] mg/L, P = 0.145), time to access removal (160 [60-220] versus 180 [90-300] d, P = 0.998), and enteral access-related complications (19% versus 16%, P = 0.21) between PEG and perc-G were similar and differences were not statistically significant. A greater percent change in prealbumin was noted for perc-G (10 [-3-20] versus 41.7% [11-65], P = 0.002).

CONCLUSIONS

Despite having higher Charlson scores and worse preoperative nutrition, there is a similar incidence of enteral access-related complications, time to goal feeds, delta prealbumin, or time to access removal between PEG and perc-G patients. Our data suggest that access approach should be made on an individual basis, accounting for anatomy and technical feasibility.

摘要

介绍

介入放射学、内镜和手术方法常用于为成年患者建立持久的肠内通路。本研究的目的是检查在接受肠内通路创建的大量患者中营养结果的差异。

方法

回顾了 2018 年至 2020 年间在一家机构接受介入放射科医生、胃肠病学家和外科医生进行肠内通路手术的成年患者。纳入的通路类型包括经皮内镜胃造口术(PEG)、开放或腹腔镜胃造口术、腹腔镜空肠造口术和经皮胃造口术(perc-G)、经皮空肠造口术或原发性胃空肠造口术。

结果

912 例符合纳入标准的患者接受了肠内通路治疗。PEG 和 perc-G 是最常见的手术。PEG 患者的 Charlson 评分较高(4.5[3.0-6.0] 与 2.0[1.0-2.0],P=0.007),白蛋白起始值较低(3.0[2.6-3.4] 与 3.6[3.5-3.8]g/dL,P<0.0001)。达到目标喂养的时间(4[2-6] 与 4[3-5]d,P=0.970)、白蛋白差值(3.6[0-6.5] 与 6.2[2.3-10]mg/L,P=0.145)、通路去除时间(160[60-220] 与 180[90-300]d,P=0.998)和肠内通路相关并发症(19%与 16%,P=0.21)在 PEG 和 perc-G 之间相似,差异无统计学意义。perc-G 的前白蛋白变化百分比更大(10[-3-20] 与 41.7%[11-65],P=0.002)。

结论

尽管 PEG 患者的 Charlson 评分较高且术前营养状况较差,但 PEG 和 perc-G 患者的肠内通路相关并发症发生率、达到目标喂养的时间、前白蛋白差值或通路去除时间无差异。我们的数据表明,应根据解剖结构和技术可行性,个体化选择通路方法。

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