Morrell D F, Harrison G G
Br J Anaesth. 1986 Apr;58(4):444-6. doi: 10.1093/bja/58.4.444.
The potential role of atracurium besylate as a trigger or attenuator of the malignant hyperthermia syndrome was tested in six MHS Landrace swine. Animals were tested for susceptibility and then exposed to atracurium given as an i.v. bolus both alone and concomitantly with 2% halothane. In no instance could the syndrome be triggered by atracurium nor did it convincingly attenuate the syndrome when triggered by halothane.
在六头患有恶性高热综合征(MHS)的长白猪身上测试了苯磺顺阿曲库铵作为恶性高热综合征触发因素或缓解因素的潜在作用。对动物进行易感性测试,然后单独静脉推注苯磺顺阿曲库铵以及同时静脉推注2%氟烷后对其进行观察。在任何情况下,苯磺顺阿曲库铵都不会引发该综合征,当由氟烷引发该综合征时,它也没有令人信服地减轻该综合征。