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髋关节融合转换为全髋关节置换术后的临床结果和并发症:系统评价和荟萃分析。

Clinical Outcomes and Complications Following Hip Fusion Conversion to Total Hip Arthroplasty: A Systematic Review and Meta-Analysis.

机构信息

Orthopedics Research Center, Ghaem Hospital, Mashhad University of Medical Sciences, Mashhad, Iran.

Faculty of Health, Department of Epidemiology, Mashhad University of Medical Sciences, Mashhad, Iran.

出版信息

J Arthroplasty. 2024 Jan;39(1):261-268.e36. doi: 10.1016/j.arth.2023.07.021. Epub 2023 Aug 3.

Abstract

BACKGROUND

Efficacy, clinical outcomes, and complications following hip fusion conversion to total hip arthroplasty (THA) surgery have been explored in several studies with controversial findings and no consensus.

METHODS

Comprehensive search of online databases was performed through December 2022 for prepost clinical trials using MeSH keywords. Harris hip score (HHS), leg length discrepancy (LLD), pain score, and range of motion (ROM) were considered as clinical outcomes along with implant survival and complications. The retrieved studies were assessed for methodologic quality. Weighted mean difference (WMD) with 95% confidence interval (CI) were calculated using random effects meta-analysis taking into account for heterogeneity. Subgroup meta-analysis as well as sensitivity analysis were performed.

RESULTS

Findings of meta-analysis on 34 trials showed that HHS increase after THA (WMD: 42.3; 95% confidence interval (CI): 38 to 47). Subgroup analyses indicated that cementless prosthesis, length of arthrodesis <12 years, age <45 years, and studies with good quality have more HHS improvement. The LLD decreased 21 mm (95% CI: 19 to 24 mm) based on 21 trials. The range of motion (ROM) reached to 89 (95% CI: 84 to 95) for flexion, 32 (95% CI: 27 to 37) for abduction, 25 (95% CI: 21 to 29) for adduction, 29 (95% CI: 25 to 33) for external rotation, and 25 (95% CI: 20 to 31) for internal rotation after surgery. The most common complication was heterotopic ossification (14%).

CONCLUSION

Conversion of an ankylosed hip to THA leads to improved hip function and leg discrepancy with relatively notable rate of complications. Our findings could provide a framework to guide surgeons and decision makers.

摘要

背景

已有多项研究探讨了髋关节融合转换为全髋关节置换术(THA)后疗效、临床结果和并发症,但研究结果存在争议,尚未达成共识。

方法

通过在线数据库的全面搜索,使用 MeSH 关键词检索了截至 2022 年 12 月的前后对照临床试验。Harris 髋关节评分(HHS)、下肢长度差异(LLD)、疼痛评分和活动范围(ROM)被认为是临床结果,同时还考虑了假体存活率和并发症。对检索到的研究进行了方法学质量评估。采用随机效应荟萃分析,考虑到异质性,计算加权均数差(WMD)及其 95%置信区间(CI)。进行了亚组荟萃分析和敏感性分析。

结果

对 34 项试验的荟萃分析结果表明,THA 后 HHS 增加(WMD:42.3;95%CI:38 至 47)。亚组分析表明,非骨水泥假体、融合长度<12 年、年龄<45 岁以及质量较高的研究具有更大的 HHS 改善。21 项试验表明 LLD 减少 21mm(95%CI:19 至 24mm)。手术中屈曲达到 89°(95%CI:84 至 95),外展 32°(95%CI:27 至 37),内收 25°(95%CI:21 至 29),外旋 29°(95%CI:25 至 33),内旋 25°(95%CI:20 至 31)。最常见的并发症是异位骨化(14%)。

结论

将僵硬的髋关节转换为 THA 可改善髋关节功能和下肢差异,且并发症发生率相对较高。我们的研究结果可为外科医生和决策者提供指导框架。

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