Department of Otolaryngology-Head and Neck Surgery, Xiangya Hospital, Central South University, 87 Xiangya Road, Changsha, Hunan, People's Republic of China.
Otolaryngology Major Disease Research Key Laboratory of Hunan Province, Changsha, Hunan, People's Republic of China.
J Robot Surg. 2023 Oct;17(5):2537-2546. doi: 10.1007/s11701-023-01689-6. Epub 2023 Aug 4.
To compare the effectiveness of transoral robotic surgery (TORS) and non-robotic surgeries (NRES) in patients with oropharyngeal squamous cell carcinoma (OPSCC), medical databases were searched including PubMed, Web of Science, Medline, Embase, and Cochrane Library up to January 2023. The methodology follows PRISMA guidelines, including the PRISMA flow diagram. Data from the included studies were extracted independently by two researchers. Seven studies involving five hundred seventy-seven patients were included. Of these, 275 underwent TORS and 302 underwent NRES. The disease-free survival rate was significantly higher in the TORS group than in the NRES group (OR = 3.43, 95% CI 1.92-6.15, P < 0.0001). However, there were no significant differences in positive surgical margins, hospital stays, operation time, blood loss, postoperative bleeding rate, perioperative tracheostomy, perioperative feeding tube, and overall survival rate. These findings can initially guide the preoperative counseling of TORS in patients with OPSCC, and preliminarily confirm that the adoption of TORS deserves careful consideration.
为了比较经口机器人手术（TORS）和非机器人手术（NRES）在口咽鳞状细胞癌（OPSCC）患者中的疗效，检索了包括 PubMed、Web of Science、Medline、Embase 和 Cochrane Library 在内的医学数据库，检索时间截至 2023 年 1 月。该方法遵循 PRISMA 指南，包括 PRISMA 流程图。由两名研究人员独立提取纳入研究的数据。共纳入 7 项研究，涉及 577 例患者。其中 275 例行 TORS，302 例行 NRES。TORS 组的无病生存率显著高于 NRES 组（OR=3.43，95%CI 1.92-6.15，P<0.0001）。然而，两组在阳性切缘、住院时间、手术时间、出血量、术后出血率、围手术期气管切开术、围手术期喂养管和总生存率方面无显著差异。这些发现可以初步指导 OPSCC 患者 TORS 的术前咨询，并初步证实 TORS 的采用值得仔细考虑。
