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对体温进行分类,并观察其对急性心肌梗死患者的影响。

Triage body temperature and its influence on patients with acute myocardial infarction.

机构信息

Department of Emergency Medicine, College of Medicine, National Cheng Kung University Hospital, National Cheng Kung University, Tainan, 70403, Taiwan.

School of Medicine, College of Medicine, National Sun Yat-sen University, 804, No.70, Lien-hai Rd, Kaohsiung, 804, Taiwan.

出版信息

BMC Cardiovasc Disord. 2023 Aug 4;23(1):388. doi: 10.1186/s12872-023-03372-y.

Abstract

BACKGROUND

Fever can occur after acute myocardial infarction (MI). The influence of body temperature (BT) after hospital arrival on patients with acute MI has rarely been investigated.

METHODS

Patients who were diagnosed with acute MI in the emergency department (ED) of a tertiary teaching hospital between 1 January 2020 and 31 December 2020 were enrolled. Based on the tympanic temperature obtained at the ED triage, patients were categorized into normothermic (35.5°C-37.5°C), hypothermic (< 35.5°C), or hyperthermic (> 37.5°C) groups. The primary outcome was in-hospital cardiac arrest (IHCA), while the secondary outcomes were adverse events. Statistical significance was set at p < 0.05.

RESULTS

There were 440 enrollees; significant differences were found among the normothermic (n = 369, 83.9%), hypothermic (n = 27, 6.1%), and hyperthermic (n = 44, 10.0%) groups in the triage respiratory rate (median [IQR]) (20.0 [4.0] cycles/min versus 20.0 [4.0] versus 20.0 [7.5], p = 0.009), triage heart rate (88.0 [29.0] beats/min versus 82.0 [28.0] versus 102.5 [30.5], p < 0.001), presence of ST-elevation MI (42.0% versus 66.7% versus 31.8%, p = 0.014), need for cardiac catheterization (87.3% versus 85.2% versus 72.7%, p = 0.034), initial troponin T level (165.9 [565.2] ng/L versus 49.1 [202.0] versus 318.8 [2002.0], p = 0.002), peak troponin T level (343.8 [1405.9] ng/L versus 218.7 [2318.2] versus 832.0 [2640.8], p = 0.003), length of ICU stay (2.0 [3.0] days versus 3.0 [8.0] versus 3.0 [9.5], p = 0.006), length of hospital stay (4.0 [4.5] days versus 6.0 [15.0] versus 10.5 [10.8], p < 0.001), and infection during hospitalization (19.8% versus 29.6% versus 63.6%, p < 0.001) but not in IHCA (7.6% versus 14.8% versus 11.4%, p = 0.323) or any adverse events (50.9% versus 48.1% versus 63.6%, p = 0.258). Multivariable analysis showed no significant association of triage BT with IHCA or any major complication.

CONCLUSION

Triage BT did not show a significant association with IHCA or adverse events in patients with acute MI. However, triage BT could be associated with different clinical presentations and should warrant further investigation.

摘要

背景

急性心肌梗死(MI)后可出现发热。体温(BT)在到达医院后对急性 MI 患者的影响很少被研究。

方法

在 2020 年 1 月 1 日至 2020 年 12 月 31 日期间,在一家三级教学医院的急诊科(ED)被诊断为急性 MI 的患者被纳入研究。根据 ED 分诊时获得的鼓膜温度,患者被分为正常体温(35.5°C-37.5°C)、低体温(<35.5°C)和高热(>37.5°C)组。主要结局是院内心搏骤停(IHCA),次要结局是不良事件。统计显著性设为 p<0.05。

结果

共纳入 440 名患者;在正常体温组(n=369,83.9%)、低体温组(n=27,6.1%)和高热组(n=44,10.0%)中,分诊呼吸频率(中位数[IQR])(20.0[4.0] 次/分钟比 20.0[4.0]比 20.0[7.5],p=0.009)、分诊心率(88.0[29.0] 次/分钟比 82.0[28.0]比 102.5[30.5],p<0.001)、ST 段抬高型心肌梗死(STEMI)的发生率(42.0%比 66.7%比 31.8%,p=0.014)、需要进行心脏导管检查(87.3%比 85.2%比 72.7%,p=0.034)、初始肌钙蛋白 T 水平(165.9[565.2]ng/L 比 49.1[202.0]ng/L 比 318.8[2002.0]ng/L,p=0.002)、峰值肌钙蛋白 T 水平(343.8[1405.9]ng/L 比 218.7[2318.2]ng/L 比 832.0[2640.8]ng/L,p=0.003)、ICU 住院时间(2.0[3.0]天比 3.0[8.0]天比 3.0[9.5]天,p=0.006)、住院时间(4.0[4.5]天比 6.0[15.0]天比 10.5[10.8]天,p<0.001)和住院期间感染(19.8%比 29.6%比 63.6%,p<0.001)的差异有统计学意义,但 IHCA(7.6%比 14.8%比 11.4%,p=0.323)或任何不良事件(50.9%比 48.1%比 63.6%,p=0.258)发生率无统计学差异。多变量分析显示,分诊 BT 与 IHCA 或急性 MI 患者的任何主要并发症均无显著关联。

结论

分诊 BT 与急性 MI 患者的 IHCA 或不良事件无显著关联。然而,分诊 BT 可能与不同的临床表现有关,需要进一步研究。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a068/10403904/45d29ad1c3b8/12872_2023_3372_Fig1_HTML.jpg

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