Respiratory Epidemiology and Clinical Research Unit, Research Institute of the McGill University Health Centre, 5252 De Maisonneuve, Room 3D.62, Montreal, Quebec, H4A 3S5, Canada.
Respiratory Epidemiology and Clinical Research Unit, Research Institute of the McGill University Health Centre, 5252 De Maisonneuve, Room 3D.62, Montreal, Quebec, H4A 3S5, Canada.
Immunol Allergy Clin North Am. 2022 Aug;42(3S):e1-e12. doi: 10.1016/j.iac.2023.05.002. Epub 2023 Jul 11.
Non-pharmacologic treatment is a vital, yet often under-utilized aspect of care for patients with ACO. As patients with ACO are often excluded from clinical trials, management decisions should be based on patient characteristic "phenotypes," such as dyspnea or exacerbation, and considering whether COPD or asthma is more pronounced in the individual patient. Self-management interventions in asthma and COPD have an overwhelming amount of supporting evidence and should be an integral part of ACO management. Additionally, pulmonary rehabilitation has widespread benefits in patients with COPD as well as asthma and should be offered in symptomatic patients with ACO. While the COVID-19 pandemic has highlighted some shortcomings, and introduced several challenges, to the delivery of PR world-wide, it has also presented the opportunity for the development and refinement of new models to deliver PR, such as telerehabilitation. While further research and development are necessary, telerehabilitation offers a promising alternative to reach patients, such as those with ACO, who would benefit from the programming. While future research is needed, we can make a more explicit and judicious use of current best evidence in making therapeutic decisions that includes non-pharmacological interventions in patients with ACO.
非药物治疗是 ACO 患者护理中至关重要但经常未被充分利用的方面。由于 ACO 患者通常被排除在临床试验之外,因此管理决策应基于患者特征“表型”,例如呼吸困难或恶化,并考虑 COPD 或哮喘在个体患者中更为明显。哮喘和 COPD 的自我管理干预措施有大量的支持证据,应该是 ACO 管理的一个组成部分。此外,肺康复在 COPD 以及哮喘患者中具有广泛的益处,应该在有症状的 ACO 患者中提供。虽然 COVID-19 大流行突出了全球 PR 服务提供方面的一些缺点,并带来了一些挑战,但它也为开发和完善新的 PR 模式提供了机会,例如远程康复。虽然需要进一步的研究和开发,但远程康复为患者提供了有希望的替代方案,例如那些受益于该计划的 ACO 患者。虽然需要进一步的研究,但我们可以更明确和明智地利用当前最佳证据做出治疗决策,其中包括非药物干预措施。