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仅累及口腔牙龈的线性 IgA 病的不寻常病例:病例报告。

An unusual case of linear IgA disease affecting only the oral gingiva: a case report.

机构信息

Department of VIP Service Center, Stomatological Hospital, Southern Medical University, 366# Southern Jiangnan Road, Guangzhou, 510280, Guangdong, China.

Department of Oral Pathology, Stomatological Hospital, Southern Medical University, Guangzhou, 510280, Guangdong, China.

出版信息

BMC Oral Health. 2023 Aug 5;23(1):541. doi: 10.1186/s12903-023-03250-1.

DOI:10.1186/s12903-023-03250-1
PMID:37543641
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10403837/
Abstract

BACKGROUND

We present a case report on desquamative gingivitis diagnosed as linear IgA disease (LAD), which is a rare autoimmune bullous disease exclusively affecting the oral gingiva. The oral mucosa can be impacted by various autoimmune bullous diseases, and our report focuses on this particular manifestation of LAD.

CASE PRESENTATION

This patient presented with atypical symptoms, as frequent blister formation on the gingiva was the primary clinical manifestation. A combination of systemic and local treatment was administered to the patient. Following the treatment, there was a significant improvement observed in both the erythema and the bullous lesions on the gingiva.

CONCLUSIONS

A more suitable local treatment strategy should be formulated for patients presenting with oral topical lesions, which clinicians can employ effectively.

摘要

背景

我们报告了一例诊断为线性 IgA 病(LAD)的剥脱性龈炎病例,这是一种罕见的自身免疫性大疱病,仅影响口腔牙龈。各种自身免疫性大疱病均可影响口腔黏膜,我们的报告重点介绍 LAD 的这种特殊表现。

病例介绍

该患者表现出非典型症状,频繁在牙龈上形成水疱是主要的临床特征。对患者进行了全身和局部联合治疗。治疗后,牙龈红斑和水疱病变明显改善。

结论

对于出现口腔局部病变的患者,应制定更合适的局部治疗策略,临床医生可以有效地应用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9afd/10403837/20b2284d6d18/12903_2023_3250_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9afd/10403837/20b2284d6d18/12903_2023_3250_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9afd/10403837/20b2284d6d18/12903_2023_3250_Fig1_HTML.jpg

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Updates in the Diagnosis and Management of Linear IgA Disease: A Systematic Review.线性 IgA 病的诊断和治疗进展:系统评价。
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