Canzler E, Böhme G, Morenz J, Röse I
Zentralbl Gynakol. 1986;108(3):167-74.
Pregnancy impairment in mice with abortion and fetal resorption was caused by rabbit antibodies to total mitochondrial, mitochondrial membrane and microsomal fractions of mouse placentas injected intraperitoneally at 12-14 days of gestation. Antibodies to cytosol and soluble mitochondrial constituents were ineffective. According to the marker distribution in the biologically active and inactive fractions membrane-bound antigens are thought to be responsible for the abortigenic effect.
妊娠12 - 14天时腹腔注射兔抗小鼠胎盘总线粒体、线粒体膜和微粒体组分的抗体，可导致小鼠出现流产和胚胎吸收，造成妊娠障碍。抗细胞质和可溶性线粒体成分的抗体则无效。根据生物活性和非活性组分中的标志物分布情况，推测膜结合抗原是造成流产效应的原因。
