Department of Child Health, College of Medicine, King Khalid University, Abha, Saudi Arabia.
Department of Family and Community Medicine, College of Medicine, King Khalid University, Abha, Saudi Arabia.
Medicine (Baltimore). 2023 Aug 4;102(31):e34475. doi: 10.1097/MD.0000000000034475.
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has less of an impact among the babies and teenagers, than it does on adults as a whole. Children turned out to be less symptomatic during the coronavirus disease (COVID-19) surge worldwide. Researchers discovered the ways of protection by preemptive care, like, treatment, variants, vaccination, social distancing, and cohorting among children as soon as their medical and epidemiological factors were assessed while being exposed to SARS-CoV-2 transmission. The actual pervasiveness of asymptomatic SARS-CoV-2 contagion is possibly undervalued because of less examination of the asymptomatic children. A half of young-aged people who tested SARS-CoV-2 positive don't show any symptoms as per the study of serology. Nevertheless, there is wide circulation of information reporting a post-infectious acute illness known as multisystem inflammatory syndrome in children (MIS-C) or multisystem hyperinflammatory syndrome. Therefore, we undertook this narrative review to synthesize the evidence from existing studies to assess the relationship between SARS-CoV-2 infections and MIS-C among Children. We reviewed PubMed, Science Direct, and Google Scholar to find the pertinent scientific papers published in English that were available for such analysis. The main purpose of this article is to present, on this limited topic, a better-comprehended review covering pertinent material and data to be informed on SARS-CoV-2 infections and MIS-C among Children.
严重急性呼吸综合征冠状病毒 2(SARS-CoV-2)对婴儿和青少年的影响比对成年人的整体影响要小。在全球冠状病毒病(COVID-19)疫情中,儿童的症状表现较少。研究人员发现了通过预防保健、治疗、变异、疫苗接种、社交距离和群体隔离等方式保护儿童的方法,一旦儿童在接触 SARS-CoV-2 传播时对其医学和流行病学因素进行评估,就可以采取这些措施。由于对无症状儿童的检查较少,无症状 SARS-CoV-2 感染的实际普遍性可能被低估了。根据血清学研究,一半的 SARS-CoV-2 检测呈阳性的年轻人没有任何症状。然而,有大量信息报告称,一种称为儿童多系统炎症综合征(MIS-C)或多系统炎症综合征的感染后急性疾病广泛传播。因此,我们进行了这项叙述性综述,以综合现有研究中的证据,评估 SARS-CoV-2 感染与儿童 MIS-C 之间的关系。我们在 PubMed、Science Direct 和 Google Scholar 上搜索了以英文发表的、可用于此类分析的相关科学论文。本文的主要目的是在这个有限的主题上提出一个更好理解的综述,涵盖相关的材料和数据,以了解 SARS-CoV-2 感染与儿童 MIS-C 之间的关系。