Department of Gastroenterology, Affiliated Hospital of Qingdao University, Qingdao, Shandong 266000, P.R. China.
The Fourth Department of the Digestive Disease Center, Suining Central Hospital, Suining, Sichuan 629000, P.R. China.
Arch Iran Med. 2023 Mar 1;26(3):172-175. doi: 10.34172/aim.2023.26.
Inflammatory bowel disease (IBD) is associated with body composition changes, which are associated with clinical prognosis, response to therapy, and quality of life in IBD patients. Therefore, it is critical to review the body composition distribution in IBD, summarize the potential factors affecting body composition distribution, and take steps to improve the body composition distribution of IBD patients as early as possible. In the current review, we searched PubMed via keywords 'inflammatory bowel disease', or 'IBD', or 'Crohn's disease', or 'CD', or 'ulcerative colitis', or 'UC', and 'body composition'. Malnutrition and sarcopenia are common in IBD patients and are associated with the clinical course, prognosis, and need for surgery. Disease activity, reduced nutrition intake, vitamin D deficiency, and intestinal dysbiosis are factors contributing to changed body composition. Early use of biological agents to induce remission is critical to improving body composition distribution in IBD patients, supplementation of vitamin D is also important, and moderate physical activity is recommended in IBD patients with clinical remission.
炎症性肠病（IBD）与人体成分变化有关，这些变化与 IBD 患者的临床预后、治疗反应和生活质量有关。因此，仔细审查 IBD 患者的人体成分分布，总结影响人体成分分布的潜在因素，并尽早采取措施改善 IBD 患者的人体成分分布至关重要。在本次综述中，我们通过关键词“炎症性肠病”或“IBD”或“克罗恩病”或“CD”或“溃疡性结肠炎”或“UC”和“身体成分”在 PubMed 上进行了搜索。IBD 患者常出现营养不良和肌肉减少症，与疾病进程、预后和手术需求相关。疾病活动度、营养摄入减少、维生素 D 缺乏和肠道菌群失调是导致人体成分改变的因素。早期使用生物制剂诱导缓解对于改善 IBD 患者的人体成分分布至关重要，补充维生素 D 也很重要，建议有临床缓解的 IBD 患者进行适度的身体活动。
