National Center for Spinal Disorders, Buda Health Center, Budapest, Hungary; School of PhD Studies, Semmelweis University, Budapest, Hungary.
National Center for Spinal Disorders, Buda Health Center, Budapest, Hungary; Department of Spine Surgery, Department of Orthopaedics, Semmelweis University, Budapest, Hungary.
World Neurosurg. 2023 Oct;178:e700-e711. doi: 10.1016/j.wneu.2023.07.148. Epub 2023 Aug 6.
Percutaneous cement discoplasty (PCD) was introduced to treat symptomatic vertical instability of the lumbar spine in a minimally invasive way. The aim of the present study was to analyze the complication pattern after PCD and to identify factors that predict the chance of cement leakage, reoperation, and length of hospital stay (LOS).
patients were treated with PCD within the study period. Clinical features and complications were analyzed by applying descriptive statistics, whereas perioperative factors predictive of cement leakage, reoperation, and LOS were identified by regression models.
Cement leakage rate was 30.4% in the total cohort; however, only fifth of them were symptomatic. Cement leakage itself did not have a significant influence on clinical outcome. Other complications and nonsurgical adverse events were registered only in 2.0% of cases. Age, subcutaneous fat tissue thickness, low viscosity cement, lower level of surgeon's experience and the number of operated levels were identified as risk factors of cement leakage (P < 0.01; c-index = 0.836). Type of procedure, Charlson comorbidity score, reoperation, and nonsurgical adverse events significantly increased the LOS (P < 0.01). Cement leakage, early surgical practice, and increased subcutaneous fat tissue thickness were risk factors for reoperation (P < 0.01; c-index = 0.72).
PCD is a relatively safe and effective procedure for treating spinal instability caused by advanced-stage disc degeneration characterized by vacuum phenomenon. Cement leakage is not uncommon but is only a radiologic complication without clinical consequences in most cases. On the other hand, it can increase the LOS and is a significant risk factor for reoperation.
经皮骨水泥椎间盘成形术(PCD)被引入微创治疗腰椎脊柱的症状性垂直不稳。本研究旨在分析 PCD 后的并发症模式,并确定预测骨水泥渗漏、再次手术和住院时间(LOS)机会的因素。
在研究期间,患者接受了 PCD 治疗。通过应用描述性统计分析,分析了临床特征和并发症,而通过回归模型,确定了与骨水泥渗漏、再次手术和 LOS 相关的围手术期因素。
在总队列中,骨水泥渗漏率为 30.4%;然而,只有五分之一的患者有症状。骨水泥渗漏本身对临床结果没有显著影响。其他并发症和非手术不良事件仅在 2.0%的病例中登记。年龄、皮下脂肪组织厚度、低粘度骨水泥、术者经验水平较低和手术节段数被确定为骨水泥渗漏的危险因素(P < 0.01;c 指数= 0.836)。手术类型、Charlson 合并症评分、再次手术和非手术不良事件显著增加 LOS(P < 0.01)。骨水泥渗漏、早期手术实践和增加的皮下脂肪组织厚度是再次手术的危险因素(P < 0.01;c 指数= 0.72)。
PCD 是一种相对安全有效的治疗方法,适用于晚期椎间盘退变引起的脊柱不稳定,其特征为真空现象。骨水泥渗漏并不少见,但在大多数情况下仅是一种无临床后果的放射学并发症。另一方面,它会增加 LOS,是再次手术的显著危险因素。