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退变性腰椎的运动衰减手术:骨水泥椎间盘成形术是一种安全有效的选择吗?

Motion attenuation surgery in the degenerative lumbar spine: Is cement discoplasty a safe and effective option?

作者信息

Cawley Derek T

机构信息

University of Galway, Ireland.

Mater Private Hospital, Dublin, Ireland.

出版信息

Brain Spine. 2025 Mar 4;5:104220. doi: 10.1016/j.bas.2025.104220. eCollection 2025.

Abstract

Cement discoplasty (CD) was initially described in 2015. This novel treatment involves injecting polymethylmethacrylate (PMMA) into the degenerate disc cavity. This is particularly applicable to elderly patients with disc degeneration and collapse, where restoration of disc height improves lordosis and sagittal balance, treating symptoms of degenerative scoliosis, foraminal stenosis, adjacent segment degeneration, or flatback syndrome, who would otherwise have significant risks for major spine surgery. In all cases, symptoms are associated with intradiscal vacuum phenomenon (IDVP), a radiological finding associated with advanced disc degeneration. The technique is neither a motion preserving nor fusion procedure. While cement acts best in compression, the concept of stabilising but not fusing the spine in such cases lacks certainty and clarity as to its clinical effectiveness. This narrative review discusses the concepts of this technique, 12 clinical series and four metanalyses, mostly advocating for its use, particularly where it delivers a solution with an acceptable safety profile, short length of stay and short recovery time.

摘要

骨水泥椎间盘成形术(CD)最初于2015年被描述。这种新型治疗方法涉及将聚甲基丙烯酸甲酯(PMMA)注入退变的椎间盘腔。这尤其适用于患有椎间盘退变和塌陷的老年患者,恢复椎间盘高度可改善脊柱前凸和矢状面平衡,治疗退变性脊柱侧凸、椎间孔狭窄、相邻节段退变或平背综合征的症状,否则这些患者进行脊柱大手术会有重大风险。在所有病例中,症状都与椎间盘内真空现象(IDVP)相关,这是一种与严重椎间盘退变相关的影像学表现。该技术既不是保留运动的手术,也不是融合手术。虽然骨水泥在压缩方面效果最佳,但在这种情况下稳定脊柱而非融合脊柱的概念在临床有效性方面缺乏确定性和清晰度。这篇叙述性综述讨论了该技术的概念、12个临床系列和四项荟萃分析,大多数都主张使用该技术,特别是在它能提供具有可接受安全性、短住院时间和短恢复时间的解决方案的情况下。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b687/11929939/3259d61faac2/gr1.jpg

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