Cardiovascular Department, First Affiliated Hospital of Xi'an Jiao Tong University, Xi'an 710061, China; Key Laboratory of Environment and Genes Related to Diseases, Ministry of Education, Xi'an 710061, China.
Cardiovascular Department, First Affiliated Hospital of Xi'an Jiao Tong University, Xi'an 710061, China; Key Laboratory of Environment and Genes Related to Diseases, Ministry of Education, Xi'an 710061, China.
Nutr Metab Cardiovasc Dis. 2023 Oct;33(10):1960-1968. doi: 10.1016/j.numecd.2023.06.013. Epub 2023 Jun 23.
This study was performed to investigate the effect of coffee consumption on abdominal aortic calcification (AAC) among adults with and without hypertension, diabetes, and cardiovascular diseases (CVD).
A total of 2548 participants from the National Health and Nutrition Examination Survey (NHANES) 2013-2014 were included. Coffee consumption was obtained from 24-h dietary recalls. Dual-energy X-ray absorptiometry (DXA) was used to measure the severity of AAC. In the fully adjusted model, compared with non-drinkers, high coffee consumption (≥390 g/d) was associated with higher AAC scores among participants with hypertension (β = 0.72, 95% CI: 0.21-1.22), diabetes (β = 1.20, 95% CI: 0.35-2.05), and CVD (β = 2.03, 95% CI: 0.71-3.36). We did not observe such an association among participants without hypertension, diabetes, and CVD. Furthermore, decaffeinated coffee was not associated with AAC.
In conclusion, patients with hypertension, diabetes, and CVD should focus on coffee consumption, especially caffeinated coffee, to reduce the burden of AAC.
本研究旨在调查咖啡摄入量对高血压、糖尿病和心血管疾病（CVD）患者与非患者的腹主动脉钙化（AAC）的影响。
本研究共纳入了 2013-2014 年国家健康和营养调查（NHANES）中的 2548 名参与者。咖啡摄入量通过 24 小时膳食回忆获得。双能 X 射线吸收法（DXA）用于测量 AAC 的严重程度。在完全调整的模型中，与不饮酒者相比，高血压（β=0.72，95%CI：0.21-1.22）、糖尿病（β=1.20，95%CI：0.35-2.05）和 CVD（β=2.03，95%CI：0.71-3.36）患者中，大量饮用咖啡（≥390g/d）与 AAC 评分升高相关。我们未在无高血压、糖尿病和 CVD 的参与者中观察到这种关联。此外，脱咖啡因咖啡与 AAC 无关。
总之，高血压、糖尿病和 CVD 患者应注意咖啡的摄入，尤其是含咖啡因的咖啡，以减轻 AAC 的负担。
