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Mechanism-directed combinational immunotherapies in liver cancer hold promise.

作者信息

Marshall Gregory, Cao Jian

机构信息

Rutgers Cancer Institute of New Jersey, New Brunswick, NJ, 08901, USA.

Department of Medicine, Robert Wood Johnson Medical School, Rutgers, The State University of New Jersey, New Brunswick, NJ, 08901, USA.

出版信息

Cell Mol Immunol. 2023 Nov;20(11):1395-1397. doi: 10.1038/s41423-023-01068-z. Epub 2023 Aug 7.

Abstract
摘要

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本文引用的文献

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Elevated nuclear PIGL disrupts the cMyc/BRD4 axis and improves PD-1 blockade therapy by dampening tumor immune evasion.
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Cabozantinib Enhances Anti-PD1 Activity and Elicits a Neutrophil-Based Immune Response in Hepatocellular Carcinoma.
Clin Cancer Res. 2022 Jun 1;28(11):2449-2460. doi: 10.1158/1078-0432.CCR-21-2517.
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Regorafenib Promotes Antitumor Immunity via Inhibiting PD-L1 and IDO1 Expression in Melanoma.
Clin Cancer Res. 2019 Jul 15;25(14):4530-4541. doi: 10.1158/1078-0432.CCR-18-2840. Epub 2019 Apr 2.
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Sorafenib inhibits macrophage-induced growth of hepatoma cells by interference with insulin-like growth factor-1 secretion.
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