Suppr超能文献

[急诊科老年创伤患者衰弱与预后不良的关系:一项前瞻性队列研究]

[Relationship Between Frailty and Poor Prognosis in Older Trauma Patients in the Emergency Department: A Prospective Cohort Study].

作者信息

Yang Jing, Gao Jing, Chen Xinyu, Bai Dingxi, Wu Chenxi

机构信息

School of Nursing, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China.

出版信息

Sichuan Da Xue Xue Bao Yi Xue Ban. 2023 Jul;54(4):816-823. doi: 10.12182/20230760107.

Abstract

OBJECTIVE

To explore the relationship between frailty and adverse outcomes in older trauma patients in the emergency department.

METHODS

A prospective cohort study was conducted. Older trauma patients admitted to the emergency department of three tertiary-care hospitals in Chengdu between January 2021 and August 2021 were enrolled. The patients were divided into a frailty group and a non-frailty group according to their assessment results for Trauma-Specific Frailty Index (TSFI). The end points, including falls, readmission, and deaths, were documented during the 6-month follow-up. Cox risk regression model was used to analyze the relationship between frailty and adverse outcomes in older trauma patients in the emergency department.

RESULTS

A total of 375 older trauma patients in the emergency department were enrolled, including 131 in the frailty group and 244 in the non-frailty group. After 6 months of follow-up, the incidences of falls, readmission and deaths in older trauma patients in the emergency department were 18.93%, 14.40%, and 7.73%, respectively. The incidences of falls (28.24% vs. 13.93%, =0.001), readmission (25.95% vs. 8.20%, =0.000), and deaths (12.98% vs. 4.92%, =0.005) in older trauma patients in the emergency department in the frailty group were higher than those in the non-frailty group. After adjusting for multiple confounding factors using the Cox regression model, the risks of falls (hazard ratio [ ]=1.859, 95% confidence interval [ ]: 1.070-3.230, =0.028] and readmission ( =2.920, 95% : 1.537-5.547, =0.001) were higher in the frailty group than those in the non-frailty group, but there was no significant difference in the risk of deaths between the frailty group and the non-frailty group.

CONCLUSION

Frailty is a risk factor for falls and readmissions in older trauma patients in the emergency department and the association between frailty and the risk of deaths in older trauma patients in the emergency department needs to be validated by further studies.

摘要

目的

探讨急诊科老年创伤患者中衰弱与不良结局之间的关系。

方法

进行一项前瞻性队列研究。纳入2021年1月至2021年8月期间在成都三家三级甲等医院急诊科就诊的老年创伤患者。根据创伤特异性衰弱指数(TSFI)评估结果将患者分为衰弱组和非衰弱组。在6个月的随访期间记录终点事件,包括跌倒、再入院和死亡情况。采用Cox风险回归模型分析急诊科老年创伤患者中衰弱与不良结局之间的关系。

结果

共纳入375例急诊科老年创伤患者,其中衰弱组131例,非衰弱组244例。随访6个月后,急诊科老年创伤患者的跌倒、再入院和死亡发生率分别为18.93%、14.40%和7.73%。衰弱组急诊科老年创伤患者的跌倒发生率(28.24%对13.93%,P=0.001)、再入院发生率(25.95%对8.20%,P=0.000)和死亡发生率(12.98%对4.92%,P=0.005)均高于非衰弱组。使用Cox回归模型校正多个混杂因素后,衰弱组的跌倒风险(风险比[HR]=1.859,95%置信区间[CI]:1.070 - 3.230,P=0.028)和再入院风险(HR=2.920,95%CI:1.537 - 5.547,P=0.001)高于非衰弱组,但衰弱组与非衰弱组之间的死亡风险无显著差异。

结论

衰弱是急诊科老年创伤患者跌倒和再入院的危险因素,衰弱与急诊科老年创伤患者死亡风险之间的关联需要进一步研究验证。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/950e/10442631/84bada2d3508/scdxxbyxb-54-4-816-1.jpg

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验