Dong Miao, Jiang Mei
Specialist Consultation Outpatient Service, Beijing Obstetrics and Gynecology Hospital, Capital Medical University/Beijing Maternal and Child Health Care Hospital, Beijing 100026, China.
Nursing Department, Beijing Obstetrics and Gynecology Hospital, Capital Medical University/Beijing Maternal and Child Health Care Hospital, Beijing 100026, China.
Sichuan Da Xue Xue Bao Yi Xue Ban. 2023 Jul;54(4):843-847. doi: 10.12182/20230760504.
To summarize the clinical efficacy and nursing experience of intrauterine blood transfusion (IUT) treatment for fetal anemia cases.
The clinical data of 4 fetal anemia cases receiving IUT in Beijing Obstetrics and Gynecology Hospital, Capital Medical University between 2020 and 2022 were collected. Four pregnant women aged 24-38 years were included in the study. They carried fetuses with anemia of unknown causes. The four pregnant women developed anxiety after they were informed of the diagnosis of fetal anemia. One-on-one psychological counseling before the IUT procedure and one-on-one companionship over the course of the surgery were provided for the pregnant women. In addition, they were closely monitored for blood transfusion reactions. Postprocedural observation of the puncture site and 24-hour monitoring of the newborns were also conducted.
The four pregnant women underwent 1-3 times of IUT in the second and third trimesters, with the minimum gestational age at the time of IUT being 25 weeks and the blood transfusion volume being 20-107 mL/time. Two pregnant women experienced irregular uterine contractions during IUT in the third trimester. Other than that, all other IUT treatments were successful. After IUT, there was a significant improvement in fetal hemoglobin, peak systolic velocity of the middle cerebral artery (MCA-PSV), and cardiothoracic area ratio. One case did not give birth in our hospital and the outcome of the fetus was not known. The other three fetuses achieved good outcomes.
Positive preprocedural psychological counseling for pregnant women, close intraoprocedural and postprocedural pregnancy monitoring, and the prevention of maternal and fetal complications are the key to improving the clinical efficacy of IUT and achieving a good fetal outcome.
总结宫内输血(IUT)治疗胎儿贫血病例的临床疗效及护理经验。
收集2020年至2022年在首都医科大学附属北京妇产医院接受IUT治疗的4例胎儿贫血病例的临床资料。研究纳入4例年龄在24 - 38岁的孕妇。她们所怀胎儿患有不明原因的贫血。4例孕妇在得知胎儿贫血诊断后均出现焦虑情绪。在IUT手术前为孕妇提供一对一心理辅导,并在手术过程中提供一对一陪伴。此外,密切监测输血反应。术后对穿刺部位进行观察,并对新生儿进行24小时监测。
4例孕妇在孕中期和孕晚期接受了1 - 3次IUT,IUT时最小孕周为25周,输血剂量为每次20 - 107 mL。2例孕妇在孕晚期IUT过程中出现不规律宫缩。除此之外,所有其他IUT治疗均成功。IUT后,胎儿血红蛋白、大脑中动脉收缩期峰值流速(MCA - PSV)及心胸面积比均有显著改善。1例未在我院分娩,胎儿结局未知。其他3例胎儿结局良好。
对孕妇进行积极的术前心理辅导、术中及术后密切监测妊娠情况以及预防母婴并发症是提高IUT临床疗效及实现良好胎儿结局的关键。