Kerr Margee, Tarabichi Yasir, Evans Alexander, Mapel Douglas, Pace Wilson, Carter Victoria, Couper Amy, Drummond M Bradley, Feigler Norbert, Federman Alex, Gandhi Hitesh, Hanania Nicola A, Kaplan Alan, Kostikas Konstantinos, Kruszyk Maja, van Melle Marije, Müllerová Hana, Murray Ruth, Ohar Jill, Pollack Michael, Pullen Rachel, Williams Dennis, Wisnivesky Juan, Han MeiLan K, Meldrum Catherine, Price David
Observational and Pragmatic Research Institute, Singapore, Singapore.
Optimum Patient Care, Cambridge, UK.
Lancet Reg Health Am. 2023 Jul 28;24:100546. doi: 10.1016/j.lana.2023.100546. eCollection 2023 Aug.
In this study, we compare management of patients with high-risk chronic obstructive pulmonary disease (COPD) in the United States to national and international guidelines and quality standards, including the COllaboratioN on QUality improvement initiative for achieving Excellence in STandards of COPD care (CONQUEST).
Patients were identified from the DARTNet Practice Performance Registry and categorized into three high-risk cohorts in each year from 2011 to 2019: newly diagnosed (≤12 months after diagnosis), already diagnosed, and patients with potential undiagnosed COPD. Patients were considered high-risk if they had a history of exacerbations or likely exacerbations (respiratory consult with prescribed medication). Descriptive statistics for 2019 are reported, along with annual trends.
In 2019, 10% (n = 16,610/167,197) of patients met high-risk criteria. Evidence of spirometry for diagnosis was low; in 2019, 81% (n = 1228/1523) of patients newly diagnosed at high-risk had no record of spirometry/peak expiratory flow in the 12 months pre- or post-diagnosis and 43% (n = 651/1523) had no record of COPD symptom review. Among those newly and already diagnosed at high-risk, 52% (n = 4830/9350) had no evidence of COPD medication.
Findings suggest inconsistent adherence to evidence-based guidelines, and opportunities to improve identification, documentation of services, assessment, therapeutic intervention, and follow-up of patients with COPD.
This study was conducted by the Observational and Pragmatic Research Institute (OPRI) Pte Ltd and was partially funded by Optimum Patient Care Global and AstraZeneca Ltd. No funding was received by the Observational & Pragmatic Research Institute Pte Ltd (OPRI) for its contribution.
在本研究中,我们将美国高危慢性阻塞性肺疾病(COPD)患者的管理情况与国家和国际指南及质量标准进行了比较,其中包括旨在实现COPD护理卓越标准的质量改进协作计划(CONQUEST)。
从DARTNet实践绩效登记处识别出患者,并在2011年至2019年的每一年中分为三个高危队列:新诊断患者(诊断后≤12个月)、已诊断患者和潜在未诊断COPD患者。如果患者有加重病史或可能加重病史(因呼吸问题咨询并开具了药物治疗),则被视为高危患者。报告了2019年的描述性统计数据以及年度趋势。
2019年,10%(n = 16,610/167,197)的患者符合高危标准。用于诊断的肺功能检查证据较少;2019年,81%(n = 1228/1523)的高危新诊断患者在诊断前或诊断后的12个月内没有肺功能检查/呼气峰值流量记录,43%(n = 651/1523)没有COPD症状评估记录。在高危新诊断和已诊断的患者中,52%(n = 4830/9350)没有COPD药物治疗的证据。
研究结果表明,在遵循循证指南方面存在不一致性,且在COPD患者的识别、服务记录、评估、治疗干预和随访方面存在改进机会。
本研究由观察性和实用性研究所(OPRI)私人有限公司开展,部分资金由Optimum Patient Care Global和阿斯利康有限公司提供。观察性和实用性研究所(OPRI)私人有限公司未因自身贡献而获得资金。