Kuźmiñski Andrzej, Przybyszewska Justyna, Bartuzi Zbigniew
Department of Allergology, Clinical Immunology and Internal Diseases, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Torun, Poland.
Department of Nutrition and Dietetics, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Torun, Poland.
Postepy Dermatol Alergol. 2023 Jun;40(3):377-383. doi: 10.5114/ada.2022.120449. Epub 2023 Jan 13.
Food protein induced enterocolitis syndrome (FPIES) belongs to a group of IgE-independent food allergies. It is the domain of paediatric patients, but it can also occur in adults. In this disease there is a life-threatening risk resulting from the possibility of a severe course of the disease and the development of hypovolemic shock. The disease was first defined in the mid-1970s. Knowledge about this disease is extremely low, we do not know its exact frequency, and the disease itself usually appears between 2 and 7 months of age. FPIES occurs mainly in formula-fed infants, typically 1-4 weeks after formula introduction, very rarely in breastfed infants, but may also develop in adults.
食物蛋白诱导的小肠结肠炎综合征（FPIES）属于一组非IgE介导的食物过敏。它主要发生于儿科患者，但也可发生于成人。在这种疾病中，由于病情严重及发生低血容量性休克的可能性，存在危及生命的风险。该疾病于20世纪70年代中期首次被定义。目前对这种疾病的了解极其有限，我们不清楚其确切发病率，且该病通常在2至7个月龄时出现。FPIES主要发生于配方奶喂养的婴儿，通常在引入配方奶后1 - 4周，极少发生于母乳喂养的婴儿，但也可能在成人中发病。
