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抗凝剂在支气管小细胞癌治疗中的应用

Anticoagulants in the treatment of small cell carcinoma of the bronchus.

作者信息

Stanford C F

出版信息

Thorax. 1979 Feb;34(1):113-6. doi: 10.1136/thx.34.1.113.

Abstract

The object of this study was to see if the addition of anticoagulants to a regimen of cytotoxic drugs would improve the prognosis in patients with small cell carcinoma of the bronchus. Twenty-four patients were randomly allocated to receive chemotherapy or chemotherapy plus anticoagulants. The median survival in the group receiving the anticoagulants was not improved.

摘要

本研究的目的是观察在细胞毒性药物治疗方案中添加抗凝剂是否会改善支气管小细胞癌患者的预后。24名患者被随机分配接受化疗或化疗加抗凝剂治疗。接受抗凝剂治疗组的中位生存期并未得到改善。

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本文引用的文献

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CELL TYPE AND THE NATURAL HISTORY OF LUNG CANCER.细胞类型与肺癌的自然史
JAMA. 1965 Jul 5;193:52-4. doi: 10.1001/jama.1965.03090010058016.
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Coagulation disorders in cancer. I. Clinical and laboratory studies.癌症中的凝血障碍。I. 临床与实验室研究。
Cancer. 1967 Sep;20(9):1452-65. doi: 10.1002/1097-0142(196709)20:9<1452::aid-cncr2820200912>3.0.co;2-t.
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Alkylating agents in bronchogenic carcinoma.支气管源性癌中的烷化剂。
Am J Med. 1969 Apr;46(4):516-25. doi: 10.1016/0002-9343(69)90071-0.
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Proceedings: Small cell carcinoma of the lung: staging, paraneoplastic syndromes, treatment, and survival.
Cancer. 1974 Feb;33(2):527-32. doi: 10.1002/1097-0142(197402)33:2<527::aid-cncr2820330230>3.0.co;2-r.

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