尼日利亚拉各斯大学教学医院颅内肿瘤的组织病理学模式。一项基于医院的十年回顾性研究。

Histopathologic patterns of intracranial neoplasms at Lagos University Teaching Hospital, Nigeria. A ten-year hospital-based retrospective study.

机构信息

Afe Babalola University College of Medicine and Health Sciences, Anatomic Pathology and Forensic Medicine; Lagos University Teaching Hospital, Anatomic and Molecular Pathology.

Lagos University Teaching Hospital, Department of Anatomic and Molecular Pathology.

出版信息

Afr Health Sci. 2023 Mar;23(1):492-503. doi: 10.4314/ahs.v23i1.51.

DOI:10.4314/ahs.v23i1.51

PMID:37545939

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10398483/

Abstract

BACKGROUND

The most common intracranial neoplasm worldwide is meningioma, followed by gliomas, and then pituitary adenomas. There are geographical differences in the pattern of occurrence of intracranial neoplasms.The purpose of this study is to establish the pattern of occurrence of different histological types of intracranial neoplasms with their age and sex distributions in our environment - Lagos, Nigeria.The histological patterns, age, and gender distributions of all the intracranial neoplasms diagnosed within the study period at the Department of Anatomic and Molecular Pathology, LUTH, Lagos, Nigeria were noted and analysed with SPSS version 23.

RESULT

There were 296 patients (165 females, 131 males; mean age of 37.0 years) diagnosed with an intracranial neoplasm within the study period. The most frequently diagnosed intracranial neoplasm was meningioma (105 cases; 35%, median age of 42 years, male to female ratio of 1:2.2), followed by pituitary adenoma (78 cases; 26%, median age of 47 years, male to female ratio of 1.3:1), and then gliomas (71 cases; 24%, median age of 28, male to female ratio of 1:1.39).

CONCLUSION

The result of the study shows pituitary adenoma to be more common than gliomas, unlike what is seen in Caucasians where the reverse is the case.

摘要

背景

全球最常见的颅内肿瘤是脑膜瘤，其次是神经胶质瘤，然后是垂体腺瘤。颅内肿瘤的发生模式存在地域差异。本研究旨在确定我们环境（尼日利亚拉各斯）中不同组织学类型颅内肿瘤的发生模式及其年龄和性别分布。

在尼日利亚拉各斯 LUTH 解剖与分子病理学系，记录并分析了研究期间所有颅内肿瘤的组织学模式、年龄和性别分布，使用 SPSS 版本 23。

结果

在研究期间，共诊断出 296 例（165 例女性，131 例男性；平均年龄 37.0 岁）颅内肿瘤患者。最常诊断的颅内肿瘤是脑膜瘤（105 例；35%，中位年龄 42 岁，男女比例为 1:2.2），其次是垂体腺瘤（78 例；26%，中位年龄 47 岁，男女比例为 1.3:1），然后是神经胶质瘤（71 例；24%，中位年龄 28 岁，男女比例为 1:1.39）。