Ekpene Ubong, Ametefe Mawuli, Akoto Henry, Bankah Patrick, Totimeh Teddy, Wepeba George, Dakurah Thomas
Neurosurgery Unit, Department of Surgery, Korle Bu Teaching Hospital, P.M.B KB77, Accra. Ghana.
Ghana Med J. 2018 Jun;52(2):79-83. doi: 10.4314/gmj.v52i2.3.
This study seeks to describe the pattern of intracranial tumours in Korle Bu Teaching Hospital (KBTH) based on patient demographics, clinical presentation, spatial distribution of tumour and histological findings.
The study design is retrospective and descriptive. Data was obtained from the clinical records of patients with intracranial tumours treated in our neurosurgery unit between January 2010 to December 2015, and histology reports obtained from the histopathology unit. Patients with intracranial tumours without definitive histological diagnosis were excluded.
Of the 102 histologically diagnosed brain tumours, out of 335 brain tumour cases seen in the period under review, 58 (56.9%) were females and 44 (43.1%) were males (p = 0.031). Gliomas were the commonest intracranial tumours - 39(38.2%) followed by Meningiomas 37(36.2%) and Pituitary Adenoma - 9(8.8%). Astrocytoma was the commonest type of Glioma comprising 30(77%) of the 39 cases. Meningotheliomatous meningioma was the commonest type of meningioma with 11 (29.7%) of 37 cases. Of the 39 Gliomas 17(43.6%) were males and 22(56.4%) were females, while for the Meningioma 17(46%) were males and 20(54%) were females. The commonest symptom was headache (64%) and the commonest tumour location was supratentorial (77.5%). The crude incidence rate of intracranial tumours in this study was 1.34 per 100,000 populations per year.
Gliomas are the commonest intracranial tumours seen in our series. Overall, females were more commonly affected than males in most brain tumours in this series, including both gliomas and meningiomas.
Not declared.
本研究旨在根据患者人口统计学、临床表现、肿瘤的空间分布及组织学检查结果,描述科勒布教学医院(KBTH)颅内肿瘤的模式。
本研究设计为回顾性描述性研究。数据取自2010年1月至2015年12月期间在我院神经外科接受治疗的颅内肿瘤患者的临床记录,以及从组织病理学科室获取的组织学报告。排除未得到明确组织学诊断的颅内肿瘤患者。
在本研究期间所见的335例脑肿瘤病例中,102例经组织学诊断为脑肿瘤,其中58例(56.9%)为女性,44例(43.1%)为男性(p = 0.031)。胶质瘤是最常见的颅内肿瘤——39例(38.2%),其次是脑膜瘤37例(36.2%)和垂体腺瘤9例(8.8%)。星形细胞瘤是最常见的胶质瘤类型,占39例中的30例(77%)。脑膜皮型脑膜瘤是最常见的脑膜瘤类型,占37例中的11例(29.7%)。39例胶质瘤中,17例(43.6%)为男性,22例(56.4%)为女性;而脑膜瘤中,17例(46%)为男性,20例(54%)为女性。最常见的症状是头痛(64%),最常见的肿瘤位置是幕上(77.5%)。本研究中颅内肿瘤的粗发病率为每年每10万人口1.34例。
胶质瘤是我们研究系列中最常见的颅内肿瘤。总体而言,在本系列大多数脑肿瘤中,包括胶质瘤和脑膜瘤,女性比男性更易患病。
未声明。