Patel Rutul, Mistry Anuja Mahesh, Mulukutla Venkatachalam, Prajapati Krupal
Internal Medicine, Texas Tech University Health Sciences Center, El Paso, USA.
Interventional Cardiology, The Hospitals of Providence, El Paso, USA.
Cureus. 2023 Jul 6;15(7):e41451. doi: 10.7759/cureus.41451. eCollection 2023 Jul.
Cardiac sarcoidosis (CS) is a rare multisystem disorder characterized by granulomatous infiltration of the myocardium, which can lead to significant morbidity and mortality. Its clinical manifestations range from asymptomatic conduction abnormalities to severe heart failure (HF) and sudden cardiac death. This comprehensive review aims to provide an overview of the diagnosis, clinical features, and current medical management strategies for CS. Additionally, the role of implantable cardioverter-defibrillators (ICDs) and the potential use of positron emission tomography in guiding management decisions are explored. A comprehensive understanding of the medical management of CS is essential for improving patient outcomes and guiding future research endeavors.
心脏结节病(CS)是一种罕见的多系统疾病,其特征为心肌的肉芽肿浸润,可导致严重的发病率和死亡率。其临床表现从无症状的传导异常到严重心力衰竭(HF)和心源性猝死不等。这篇综述旨在概述CS的诊断、临床特征和当前的药物治疗策略。此外,还探讨了植入式心脏复律除颤器(ICD)的作用以及正电子发射断层扫描在指导管理决策中的潜在应用。全面了解CS的药物治疗对于改善患者预后和指导未来的研究工作至关重要。