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英国皇家汉普郡医院糖尿病足诊所患者糖尿病足问题研究:单中心经验

Study of Diabetic Foot Problems Among Patients Attending the Diabetic Foot Clinic at Royal Hampshire County Hospital, United Kingdom: A Single-Centre Experience.

作者信息

Pakkiyaretnam Mayurathan, Chong Jimmy

机构信息

Department of Clinical Sciences, Faculty of Healthcare Sciences, Eastern University Sri Lanka, Batticaloa, LKA.

University Medical Unit, Teaching hospital Batticaloa, Batticaloa, LKA.

出版信息

Cureus. 2023 Jul 6;15(7):e41454. doi: 10.7759/cureus.41454. eCollection 2023 Jul.

DOI:10.7759/cureus.41454
PMID:37546080
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10404058/
Abstract

Background Patients with diabetes mellitus (DM) are on the rise all over the world. Simultaneously, the complications of DM are also increasing. Diabetes-related foot problems have been another concern among health professionals, especially foot ulcers, osteomyelitis, and amputations. Objectives We determined the prevalence of gender, age, types of DM including non-diabetics, various foot-related presentations, complications, and their outcomes. Methods A retrospective descriptive cross-sectional study was conducted among new patients attending a diabetic foot clinic over a period of six months, from January 1, 2019 to June 30, 2019. To confirm the outcome of the study, all of them were followed up for at least four months from the date of diagnosis. Results The study showed that most patients were males (65.5%). The most common age group for diabetic foot problems was 81-90 years, and about 80% of the foot problems were diagnosed in patients over 60 years. The study disclosed that 86.2% of the population had type 2 DM, 56.9% had ulcers, and 13.8% had osteomyelitis. The outcome of our study demonstrated that 65.5% of the patients were cured and discharged within four months of the diagnosis, but 10.3% of the population needed amputation. During the four-month follow-up period, 3.4% of our study population died due to non-foot-related causes. A total of 48.1% of our ulcer patients were discharged within eight weeks of diagnosis. However, 26% of ulcer patients and 75% of osteomyelitis patients needed more than four months to be discharged. Peripheral neuropathy and peripheral arterial disease (PAD) were present in 91% of ulcer patients. Among our osteomyelitis group, 100% had peripheral neuropathy, and 87.5% had PAD. About 20% of ulcer patients and none of the osteomyelitis patients were diagnosed with chronic kidney disease (CKD) stages beyond 3b. About 2/3rd of our ulcer and osteomyelitis population had an HbA1C level of more than 7.5%. Conclusion Male patients over 60 years of age with type 2 DM are more at risk of developing diabetes-related foot issues. Ulcer with or without osteomyelitis was the most common complication among our study population. Results showed that a significant amount of osteomyelitis patients underwent foot amputation. Poor glycaemic control of HbA1C of more than 7.5%, peripheral neuropathy, and PAD were the most common risk factors for developing foot-related complications. Prolonged use of antibiotics and a dedicated professional team may be needed to manage these complications successfully.

摘要

背景 糖尿病患者在全球范围内呈上升趋势。与此同时,糖尿病的并发症也在增加。糖尿病相关的足部问题一直是健康专业人员关注的另一个问题,尤其是足部溃疡、骨髓炎和截肢。

目的 我们确定了性别、年龄、糖尿病类型(包括非糖尿病患者)、各种与足部相关的表现、并发症及其结局的患病率。

方法 对2019年1月1日至2019年6月30日期间在糖尿病足诊所就诊的新患者进行了一项回顾性描述性横断面研究。为了确认研究结果,从诊断之日起对所有患者进行了至少四个月的随访。

结果 研究表明,大多数患者为男性(65.5%)。糖尿病足部问题最常见的年龄组为81 - 90岁,约80%的足部问题在60岁以上的患者中被诊断出来。研究发现,86.2%的人群患有2型糖尿病,56.9%的人有溃疡,13.8%的人有骨髓炎。我们的研究结果表明,65.5%的患者在诊断后四个月内治愈并出院,但10.3%的人群需要截肢。在四个月的随访期内,3.4%的研究人群因非足部相关原因死亡。共有48.1%的溃疡患者在诊断后八周内出院。然而,26%的溃疡患者和75%的骨髓炎患者需要超过四个月才能出院。91%的溃疡患者存在周围神经病变和外周动脉疾病(PAD)。在我们的骨髓炎组中,100%的患者有周围神经病变,87.5%的患者有PAD。约20%的溃疡患者被诊断为慢性肾脏病(CKD)3b期以上,而骨髓炎患者中无人被诊断为此类情况。约三分之二的溃疡和骨髓炎患者糖化血红蛋白(HbA1C)水平超过7.5%。

结论 60岁以上的2型糖尿病男性患者患糖尿病相关足部问题的风险更高。有或无骨髓炎的溃疡是我们研究人群中最常见的并发症。结果表明,大量骨髓炎患者接受了足部截肢。HbA1C血糖控制不佳超过7.5%、周围神经病变和PAD是发生足部相关并发症最常见的危险因素。可能需要长期使用抗生素和专业团队来成功管理这些并发症。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e0b4/10404058/9293e456d6e1/cureus-0015-00000041454-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e0b4/10404058/e28a48b812f3/cureus-0015-00000041454-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e0b4/10404058/9293e456d6e1/cureus-0015-00000041454-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e0b4/10404058/e28a48b812f3/cureus-0015-00000041454-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e0b4/10404058/9293e456d6e1/cureus-0015-00000041454-i02.jpg

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